What Does Lamivudine Treat

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Lamivudine (Epivir)

What Is Lamivudine? Lamivudine (Epivir) is a drug used as part of antiretroviral therapy (ART). It is manufactured by ViiV Healthcare. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Lamivudine is also known as 3TC. Lamivudine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse transcriptase enzyme. This enzyme changes HIV's genetic material (RNA) into the form of...

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Lamivudine and pegalated interferon for Hep B

My doctor and I are considering putting me on pegylated interferon and Lamivudine to treat my chronic active/persistent Hep B of eleven years. I just found out this year that I've developed HBeAb. I'm still HBeAg + and my viral load is...

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine

There is no data yet on that combination for hepatitis B, but it is being studied. The dose of peg interferon alfa 2b is 1.5 mcg/kg just like hep C. It depends on how much HBV DNA you have and what your liver biopsy looks like before I would treat.... Read more »

Advised to Take Lamivudine During 3rd Trimester Due to HB-Need Answer ASAP

Please reply ASAP to my questions below. I will be in my 3rd trimester this Friday, Dec. 24, 2004 and have been so worried about my baby's health because I have hepatitis B. I was tested positive for e antigen and DNA (PCR DNA indicated a...

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine

I think that is a very rational approach to take lamivudine. There is no more benign medication to take for hepatitis B. There has been over 15 years of experience with lamivudine in pregnancy in HIV patients and it does not seem to be a problem. If... Read more »

Was Advised to Take Lamivudine During 3rd Trimester-Need an Answer ASAP

Response from Barbara McGovern, M.D.

Tufts University School of Medicine

The guidelines published by the American Association for the Study of Liver Disease quote a 95 percent efficacy rate if Hepatitis B immunoglobulin and hepatitis B vaccine is given. Your infant will need to receive all doses of vaccine to be... Read more »

how long the treatment of lamivudine

How long is the treatment of lamivudine? My boyfriend was already taking it for 3 montns? Thank you very much.....

Response from Barbara McGovern, M.D.

Tufts University School of Medicine

The duration of therapy is not a set one - it depends on the response of the patient. The levels of virus in the blood and the outcome of hepatitis B e antigen are important levels to follow.... Read more »

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