What Does Indinavir Treat

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Indinavir (Crixivan)

What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy (ART). It is also called Crixivan. It is manufactured by Merck & Co. Indinavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these scissors. Who Should Take It? Indinavir was...

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Indinavir sulfate

Dear Doctor,I have a question about the dose of Indinavir sulfate.According to a book about HIV/AIDs treatment (Published by POZ organization), the dose of Indinavir is 800mg three time a day and they also put a remark on the dose of this medicine...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.Indinavir (Crixivan) can be dosed either way-- without ritonavir (Norvir) boosting, the medication is dosed every 8 hours, fasting. Indinavir should not be administered twice daily without ritonavir.With ritonavir, the... Read more »

nelfinavir+indinavir, is it possible?

Nelfinavir+indinavir, is it possible? Nelfinavir+indinavir, is itpossible?...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Yes, it's possible. Yes, it's possible. Yes, it's possible.BUT, it hasn't been tested so we wouldn't know what doses to use. Also,since nelfinavir is taken with food and indinavir is taken on an emptystomach, you'd... Read more »

pep doseage confusion Indinavir 2 or 3 times day?

Been prescribed PEP Combivir and Indinavir both at 2 doses per day.However have read here and at WHO website that Indinavir should be taken 3 times daily.Currently taking 2 times. Up dosage to three times day?many, many thanks....

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,The correct dose of indinavir is 800 mg every eight hours in a fasting state (one hour before or two hours after a meal). You should also drink at least six eight-ounce glasses of water per day (48 oz) to prevent indinavir-associated kidney... Read more »

switching from indinavir to Lopinavir/r

I have a patient has been well controlled with Indinavr+ AZT+3TC. But now Indinavir is not available. Will it be acceptable to use Lopinavir/r with same 2 NRTIs. The patient had previous exposure to Squinavir also....

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Should not be a problem at all.... Read more »

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