What Does Zidovudine Do

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Zidovudine (Retrovir, AZT)

What Is Zidovudine? Zidovudine (Retrovir) is a drug used for antiretroviral therapy (ART). It was first manufactured by GlaxoSmithKline. It is manufactured by ViiV Healthcare. The patent on zidovudine expired in 2005 and several generic versions have been approved. Several are available under PEPFAR (see Fact Sheet 475 ). Zidovudine is also known as azidodeoxythymidine, AZT or ZDV. Zidovudine was the first drug approved for the treatment of...

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developed lipoatrophy while on videx,zidovudine and aluvia

what is lipoatrophy(from 2006 on videx and zidovudine) and can it be treated and how but i'm now switched to truvada and aluvia after alerting my doctor about my fat distribution last month ...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Fat loss (lipoatrophy) and fat gain have been linked to zidovudine and somewhat less so to didanosine (Videx). Switching to Truvada and Aluvia (lopinavir/ritonavir) may stabilize the fat loss with slow recovery. Its impact on areas of fat gain is... Read more »

zidovudine

under which of the following conditions is azt (zidovudine) prescribed for patients suffering from hiv?...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Zidovudine (AZT, Retrovir) is used as part of combination therapy for the treatment of HIV-infected individuals or in special circumstances for the prevention of HIV infection, following high-risk exposure. BY... Read more »

infant zidovudine: recommendations for dose escalation with weight gain?

I know standard dosage for zidovudine for an infant born to an HIV positive mother is "2 mg/kg body weight q6h" as part of the MTCT prevention. In 6 weeks time however, an infant easily weighs a kilo, to 1.5 kg more which is up to 50% of...

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School

In our clinic, we usually see babies at 1 and 4 weeks to see how things are going, check their weights, and to draw bloods to check for infection. If weight is increased by more than 10% of the baby's previous weight, we adjust the dose. If... Read more »

atripla and zidovudine

if somebody becomes resistant to atripla components would he necessarily become resistant to zidovudine as well? i hope not because in a paper i saw point mutations caused by 3 components of atripla are absolutely different from that caused by...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thanks for posting.There is a potential for cross resistance among the components of treatment. This means that prolonged treatment failure of one NRTI regimen has the potential to cause significant cross resistant to other medications of... Read more »

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Liver Function

Posted by NYRN, 1 Reply

I'm taking viread, invirase, didanosine, zidovudine and valtrex and my latest labs indicate high on the liver screens. Has anyone had any liver issues - I don't drink so it's not that! Read more »

unprotected sex----ECLIA test

Posted by haohaode, 1 Reply

on 4 February, i had unprotected vaginal sex with a thai sex worker for less than two minutes.
within 24 hours i took Kaletra, lamivudine and zidovudine for 28 days.
on 30 March(8 weeks later), this woman had ECLIA/ Roche Diagnostics test with... Read more »

What is my overall risk of get HIV?

Posted by francisco23016, 1 Reply

Hi,

I am Rodrigo. I write because I have inquiries about risks of transmission of HIV. Three weeks ago, I had receptive and protected anal sex ( we used condom which did not break) with a guy whom has HIV (I realized of that the next morning of the... Read more »

What is my risk?

Posted by francisco23016, 1 Reply

Hi there,

I write here because I have inquiries of transmission of HIV. Two months ago, I had receptive and protected anal sex ( we used condom which did not break) with a guy whom has HIV (I realized of that the next morning of the intercourse).... Read more »

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