What Does Efavirenz Treat

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Efavirenz (Sustiva)

What Is Efavirenz? Efavirenz is a drug used as part of antiretroviral therapy (ART). It is also called Sustiva or Stocrin. It is manufactured by Bristol-Myers Squibb. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (a "non-nuke" or NNRTI). These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme...

Ask the Experts

Efavirenz pychotic side effects

My sister in zambia is on EFV,d4T and 3TC. She is taking ant TB drugs as well- intense phase. Her CD4 count is 33 and has only been on ARVs for 1 week. Before the ARVs she had 2 episodes of convulsions which led to Cryptococcal menigitis being...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Generally a patient can be treated through the early period of brain side effects from efavirenz. Otten some sort of sedative /sleep drug is offered to help out during the first several weeks when a patient is having significant problems. The... Read more »

Warfarin and Efavirenz

My dh, late 40's, is scheduled for hip surgery next week. He was dxed 2.5 years ago and started Atripla and became undetecatable within a few months. He had pre-surgical testing and education and a medical clearance visit with a cardiologist....

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

There is variable interaction between efavirenz and warfarin so more careful attention to coagulation status and HIV levels is recommended when those drugs are used together. Both HIV doc and coagulation nurse need to be informed when those drugs... Read more »

A positive story about Atripla (specifically sustiva/efavirenz) rash

This isn't a question but a story. I wanted to share my experience of starting Atripla as I've seen a lot of people posting questions about the rash.I found out I had HIV 18 months ago and started Atripla 7 months ago. A week in I...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Thanks for sharing your experience--treating through a severe rash due to an HIV medication such as efavirenz in the ATripla can be nerve-racking for the patient and caregivers since often will resolve but rarely the situation can worsen and even... Read more »

Effect of efavirenz on lansoprazole

I've been on HAART (Kivexa and efavirenz) since September 4th and had an excellent response, currently VL<40 and CD4 671 31%, from VL 120,000 and CD4 420 21% at baseline.For the past 3 years I've been treated for oesophageal reflux with...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Generally proton pump inhibitors are OK to take with efavirenz based regimens. If there is a concern an efavirenz blood level could be checked. KH... Read more »

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Efavirenz: ways to fight its sleep-reduction.

Posted by BrokenWingedBird, 1 Reply

If Efavirenz (and Efavirenz along)is really wrecking your sleep quality, then the only solution is to stop taking Efavirenz (and substitute it with another drug).

However, there are ways to ensure your sleep is as good as possible.

Important discovery: Read more »

5 lessons about the way we treat people

Posted by franfrog, 2 Replies

Five (5) lessons to make you think about the way we treat people.

1 - First Important Lesson - Cleaning Lady.

During my second month of college, our professor
gave us a pop quiz. I was a conscientious student
and had breezed through the questions until... Read more »

treating hiv holistic healthwise

Posted by taian, 2 Replies

anyone involved treating hiv with herbology,using colloidal silver regime or other w/good results Read more »

SEEKING FERTILITY DOCS WHO TREAT POSITIVE COUPLES!

Posted by Anonymous, 3 Replies

Hello Friends,

My husband and I are both positive and have been researching having a baby for 2 years. We are both healthy with undetectable viral loads and high cd4 counts and we are well aware of the risks. I know under the Americans With... Read more »

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