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What Does Didanosine Treat

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Get the Facts
AIDS InfoNet

Didanosine (Videx, ddI)

...Didanosine React With Other Drugs? What Is Didanosine? ddI (Videx) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Didanosine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse...
Ask the Experts

lipo in face on Videx

I have been taking Kaletra and Videx for a few years now but iI have noticed two holes or permanent dimples at or around my cheek areas. It is becoming a nuisance and embarrassing to me. Is there any way of treating this with no severe side effects?
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...stop the Videx, because Kaletra monotherapy is sufficient to control viral replication in many cases. You can also receive treatment with a facial filler like Sculptra or Radiesse to improve your appearance. Good luck! Read more »

developed lipoatrophy while on videx,zidovudine and aluvia

what is lipoatrophy(from 2006 on videx and zidovudine) and can it be treated and how but i'm now switched to truvada and aluvia after alerting my doctor about my fat distribution last month
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...Fat loss (lipoatrophy) and fat gain have been linked to zidovudine and somewhat less so to didanosine (Videx). Switching to Truvada and Aluvia (lopinavir/ritonavir) may stabilize the fat loss with slow recovery. Its impact on Read more »

HCV with deterating CD4 on HIV

I have been on the HCV treatment for 2 weeks now and just got my results back on my HIV CD4 and Viral Loads prior to the starting of treatment. My results were CD4 214 and VL 93050 but the HCV specialist doesn't want me to start HIV meds until the...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
...your HCV therapy first. I have done just that in patients who had hepatotoxicity from trying to take their HIV medications. Treatment of their HCV infection enabled me to then treat their HIV. I have usually done this in rapid succession (about... Read more »

Should I stay on abacavir

Have been reading about ziagen and increased incidences of heart attacks. I am a 57 y.o gay white male. Family hx of father having a fatal MI at age 58, hx of HTN and hyperlipidemia. Not a smoker, weight under control. On Atenolol and zocor with...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

...patients that have been followed with HIV for several years. A small, but significant numbers of those patients that were been treated with abacavir (Ziagen) and didanosine (Videx) were found to have a higher incidence of developing a myocardial... Read more »
The Body PRO

Abstract No. 116: Mutations in the Reverse Transcriptase Genome of HIV I Isolates Derived from Subjects Treated with Didanosine and Stavudine in Combination

...drug. These findings extend previous observations of the emergence of AZT associate mutations and isolates derived in subjects treated separately with DDI, d4T, Adefovir, and, more recently, isolates derived from subjects treated with Adefovir... Read more »
The Body PRO

Efavirenz (EFV) in Combination with Stavudine (D4T) and Didanosine (DDI) or Lamivudine (3TC) Is Well-Tolerated and Efficacious in the Majority of Patients Treated

...copies. Overall, 90% were below 50 copies at week 48 using an "on treatment" analysis, and 80% were below 50 copies using an "intent to treat" analysis. In the subset of people who had a viral load over 100,000 when starting the study, the... Read more »
U.S. Food and Drug Administration

Important Drug Warning: High Rate of Virologic Failure in Patients With HIV Infection Treated With a Once-Daily Triple NRTI Regimen Containing Didanosine, Lamivudine, and Tenofovir

...nucleoside reverse transcriptase inhibitor (NRTI) resistance-associated mutations observed in a clinical study of HIV-infected treatment-naive patients receiving a once-daily triple NRTI regimen containing didanosine enteric-coated beadlets... Read more »
U.S. Food and Drug Administration

Videx EC/Videx (Didanosine) Label Change Reflects Potential for Serious Liver Disorder

...known as non-cirrhotic portal hypertension in patients using Videx or Videx EC (didanosine). Didanosine is a medication used to treat human immunodeficiency virus (HIV) infection. Non-cirrhotic portal hypertension (portal hypertension that... Read more »
Connect With Others

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »

Controversial Subject

Posted by pozmarie, 2 Replies
I am a 29 year old woman who has been HIV poz for approx. 10 years. I have a CD4 of approx. 800 with undetectable viral load. I had one daughter young before I contracted HIV and did not get married but remained good friends with her father. Fast... Read more »


Posted by Survivor, 1 Reply
...only US$20 to US$50 a month), can make it a daunting task to find doctors, especially medical specialists, who are willing to treat people with HIV. The Ukrainian epidemic stands in stark contradiction to the stereotype that Americans hold... Read more »


Posted by Anonymous
... Home > News & Publications > Journals > AFP > Vol. 60/No. 2 (August, 1999) How to Recognize and Treat Acute HIV Syndrome BARBARA LEE PERLMUTTER, M.D., PH.D., JORDAN B. GLASER, M.D., and SAMWEL O. OYUGI, M.D. Staten... Read more »