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What Does 3TC Do

Here's a taste of what has to offer on this topic:
Get the Facts

An Overview of Epivir (3TC, Lamivudine)

... la-MI-vyoo-deen Brand Name: Epivir Other Name(s): 3TC, Epivir-HBV, Lamivudina Drug Class: Nucleoside Reverse Transcriptase Inhibitors Lamivudine, also known as Epivir or 3TC, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs block reverse transcriptase, a protein that HIV needs to make more copies of itself. HIV/AIDS-Related Uses
Ask the Experts


I am having problems with anemia again and the first time the problem was caused by AZT, now I'm on 3TC and I may be wrong but I believe that somewhere in the literature that 3TC has AZT in it. Is is true?
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hi,Nope. AZT and 3TC are two completely different drugs. What may have confused you is a drug called Combivir that contains both AZT and 3TC or a Read more »

Viread/3TC/FTC Hair loss

There seems to be some confusion about what part of Truvada might cause hair loss. I haven't seen anything that implicates FTC other than it's similarity to 3TC. In your opinion, is Viread the more likely culprit? Also, if it is more likely FTC,...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia the tenofovir. A way of testing if that is the case would be to switch from the tenofivir/FTC combination to the abacavir/3TC combination (Epzicom or Kivexa, depending on where it is sold), and see what happens. Your combination will still... Read more »

Viread+3TC+EFV vs AZT+3TC+EFV

Dear doctors,I'm on Gilead "extended" 903 clinical trial, finishing in 3 months' time. My medical insurance has told me that they will not provide me with VIREAD, since that drug is only provided to all-drug-resistant patients.Could my current...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
One of the reasons that we do research studies is to determine optimal therapy. The 903 study demonstrated the superiority of Viread over d4T and clearly supports its use in first-line therapy. If your insurance company is denying it, this is... Read more »

Hair Loss & 3TC - Switch 1 of 3 Drugs? JB

I've been on Crix, AZT & 3TC since 1996 and have had an undetectable viral load and increasing CD 4 count to 550+. But in the last 6 months I been losing my hair. I would like to stop 3TC, but I don't know which drug I should substitute for the 3TC?...
John A. Bartlett, M.D.

Response from John A. Bartlett, M.D.

Duke University Medical Center
Hair loss can occur in persons with HIV infection, both on or off of antiretroviral therapy. Recently Crixivan has been linked with hair loss, and my guess is that it may be responsible for yours. I might start by switching your Crixivan to... Read more »
The Body PRO

Session 50, Abstract 377: d4T+3TC versus AZT+3TC

... Shattering the synergy story A number of trials showed that the combination of d4T+3TC is at least aseffective as AZT+3TC, suggesting that d4T may be more attractive than AZT aspart of a combination therapy regimen Read more »
The Body PRO

Late Breaker No. LB16: Phase III, Multicenter, Randomized, Open-Label Study to Compare the Antiretroviral Activity and Tolerability of Efavirenz (EFV) + Indinavir (IDV), versus EFV + Zidovudine (ZDV) + Lamuvidine (3TC), versus IDV + ZDV + 3TC at 48 Weeks (Study DMP 266-006)

...durability of plasma antiviral response to multidrug therapy with EFV. This study enrolled 450 participants who were PI, NNRTI and 3TC treatment naïve, and who had baseline CD4 of 354  +  202 cells/mm 3 , and RNA PCR of 4.77  +  0.57 log... Read more »
The Body PRO

Session 50, Abstract 379: Combination Therapy with AZT + 3TC + Indinavir vs. d4T + 3TC + Indinavir in Pretreated Patients with Less than 200 CD4/mm 3

...In this non-randomized study, Dr. Rubio and colleagues looked at the efficacy and tolerance of combination therapy with AZT + 3TC + indinavir as compared to d4T + 3TC + indinavir. They enrolled forty-four pre-treated patients (either AZT and/or... Read more »
The Body PRO

Poster Session 22339: A Comparison Between Seminal Plasma RNA and Blood Plasma RNA in HIV+ Men Who Receive Either Zidovudine (ZDV) Plus Lamuvidine (3TC) or ZDV Plus 3TC Plus Indinavir

...medications. The study enrolled 15 men with CD4 cell counts below 200, at least 6 months of ZDV (AZT) use, and no prior indinavir or 3TC use, and randomized then to a double-blinded regimen of either AZT/3TC/placebo or AZT/3TC/indinavir. Ten... Read more »
Connect With Others

Reyataz,Norvir, Kivexa [abacavir/3TC, Epzicom].

Posted by Mondo
...anyone here at the forum taking the following cocktail? I'm taking Reyataz[atazanavir], Norvir [ritonavir] and Kivexa [abacavir/3TC, Epzicom]. I would be interested to know how you are going with it and any problems or side effects that you may... Read more »

about to start treatment

Posted by Anonymous, 4 Replies
...induction/maintenance strategy starting with an intense four-drug Kaletra (LPV/r, lopinavir/ritonavir)-based regimen along with Combivir [AZT/3TC] + Viread [tenofovir]. can you tell me side effects with these? also is facial lipotrophy a side... Read more »

I am HIV + and anemic

Posted by Anonymous
... I am HIV + and am anemic. My T-cell count is 176 , viral load undetectable. I am taking AZT/3TC, Viramune, Bactrim B-6, and INH . I was recently admitted to the hospital and received 4 units of blood. I am holding my own Read more »


Posted by Anonymous, 2 Replies
Does anyone have any experience with viread? I hear it's supposed to be great in terms of side effects, but I want to know if anyone went on it either a switch or new reg and noticed increased lipo or new lipo or hair loss? Read more »