What Do Integrase Inhibitors Treat

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Ask the Experts

New Integrase inhibitor and lipodystrophy risk

There is a once a day integrase inhibitor with a non-PI booster coming up soon, isn't there? What is the integrase inhibitor called and what class does the booster belong to? Setting aside the relative newness of these drugs (and therefore the...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

Hello and thanks for posting. The new integrase inhibitor medication is called elvitegravir and the booster is GS 9350. The booster is one of a new class of drugs designed specifically to inhibit the CYP3A liver enzyme system. We already know that... Read more »

integrase inhibitors,where are they?

Dr. Frascino, I know we know of three crucial enzymes necessary for HIV to do its dirty work.... Read more »

Response from Robert J. Frascino, M.D. »

Integrase inhibitor

Hello doctor,Any possibility dolutegravir could to be used as Monotherapy even though there's... Read more »

Response from Benjamin Young, M.D., Ph.D. »

Go to Ask the Experts »

Articles

Comparing Two Integrase Inhibitors

It was more than a wish that integrase inhibitors became weaponry against HIV. We've waited a long time to get to this point and an even longer time to arrive at the position where we're now studying and comparing two integrase inhibitors.... Read more »

ViiV Announces Expanded Access to Once-a-Day Integrase Inhibitor ... But Activists Are Concerned About Its Potential Misuse

The dolutegravir expanded access program (EAP) has been designed to provide free access to Shionogi-ViiV Healthcare's investigational integrase inhibitor, dolutegravir (DTG, S/GSK1349572) in an open-label protocol program to adults living with HIV... Read more »

Canadian AIDS Treatment Information Exchange

Integrase Inhibitor '572 Tested Against Raltegravir-Resistant HIV

GlaxoSmithKline (GSK) has licensed an anti-HIV integrase inhibitor discovered by the Shionogi Corporation in Japan. Because of these arrangements, this drug has the complex code name S/GSK1349572 and for now is increasingly referred to simply as... Read more »

New Experimental Drug Integrase Inhibitor (MK-0518)

For the last six years, treatment has driven the AIDS agenda. Just this past summer, the Food and Drug Administration (FDA) approved Prezista, a new Protease Inhibitor, as well as Atripla, the first once-daily single tablet regiment for adults with... Read more »

Connect With Others

Integrase Inhibitor

Posted by Survivor

I just wanted people realize there is hope and continued very active DRUG DISCOVERY!

Merck, Gilead Release Strong Findings From Clinical Trials of Experimental Integrase Inhibitor Antiretroviral Drugs

Whitehouse Station, N.J.-based Merck and Foster... Read more »

Today's LA Times Article - Integrase Inhibitors

Posted by Anonymous

Very hopeful! (Despite the sad title.)

http://www.latimes.com/news/nationworld/nation/la-me-salvage2jan02,0,1565232,full.story?coll=la-home-headlines Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply

Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

AbacavirLamivudine to treat HIV infection.

Posted by jenniferdraper

AbacavirLamivudine is used to treat HIV infection. This combination medication is used with other medications. It belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors. Read more »

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