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What Cells Are Affected Directly By Hiv

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AIDS InfoNet

CD4 Cell Tests

...T-8 cells (CD8+) are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected with a virus. Researchers can tell these cells apart by specific proteins on the cell surface. A T-4 cell is a T-cell with CD4 molecules on its surface. This type of T-cell is also called "CD4 positive," or CD4. Why Are CD4 Cells Important in HIV? When HIV infects humans, the cells it...
Ask the Experts

HIV attacks CD8 cells?

My Drs. can't answer this and my lengthy internet searches are fruitless. I know all about how HIV attacks CD4s, but does it also infect/hijack CD8s? Thank you!
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...Unlikely to infect CD8 cells, unless they are dual positive CD4/CD8, of which there are a few. On the other hand, infecting CD4 cells and destroying them Read more »

t cell transfusion

I understand that HIV directly affects the helper t cell population. And that t cells are necessary to stimulate B cells, B cells to differentiate into plasma cells, finally secreting antibodies. Of course as time passes, the virus depletes the t...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...That is a great question. Unfortunately giving t cells to someone with HIV is like giving them an organ transplant. The t cells would be recognized as foreign and would be destroyed. Read more »

Eliminating HIV reservoirs might damage cells?

Dear Dr. Wohl:Once you said in this forum that the researcher (I cant remember his name) who did the study on valproic acid is working at your university.Imagine his theory worked and he could figure something to force the virus to leave the cells...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...from replicating. These resting cells are mostly in lymph tissue. Whether there are resting cells in the brain that could be affected by valproic acid and, if so, can that in a way lead to harm, I do not know and will ask my colleague and get... Read more »

Blood for T cell test taken during glucose tolerance test: could it affect the results of the T cell test?

Dr.Moyle,During a glucose tolerance test (I was actually having it done per your recommendation), they drew blood for a T cell subset. I was to have had a T cell subset done late next week, but I thought that, since they had the needle in my vein...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
it should make no difference. There are many things reported to modestly influence CD4 and VL tests but fed and fasted states are not one that is considered important. Vigourous excercise, smoking, infections and vaccinations are the most well known... Read more »
Articles
University Hospital Heidelberg

How HIV Cripples Immune Cells

...stopped completely. The underlying mechanism of this observation was a complete mystery up to now, however. HIV modifies the cell structure system of the host cells Viruses alter the support structures of affected cells, enabling them to... Read more »
The Well Project

Understanding CD4 Cells and CD4 Cell Tests

... The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood Read more »
University of California-Los Angeles

UCLA Researchers Demonstrate That Stem Cells Can Be Engineered to Kill HIV

... Researchers from the UCLA AIDS Institute and colleagues have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells -- a process that potentially could be used against Read more »
Gay Men's Health Crisis

Anal Cancer, HIV and Gay/Bisexual Men

...arriving within the next few months. In MSM, a clear relationship has not yet been determined between a high DNA HPV load and the cell changes that lead to anal cancer, but if confirmed, this test will become more widely used in the future. Then,... Read more »
Connect With Others

White Blood Count Question

Posted by Anonymous, 4 Replies
...When you get a standard blood workup from the doctor and they say your white blood cell count is elevated would that correspond to a recent HIV exposure? I was not sure if an HIV exposure would cause a decreae in Read more »

More Promise for Hope

Posted by Survivor, 2 Replies
...infected in the laboratory with a harmless mouse virus engineered to carry the ribozyme gene. The genes are a blueprint that tell the cell how to make the enzyme. Three days after the gene is transferred to the stem cells, they are returned to... Read more »

See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply
...However, the problem is not free virus, but the fact that the viral RNA has become incorporated into the DNA of CD4 cells and other human cells. As long as those cells are alive, the virus is safe and capable of ... Read more »

What do you think?

Posted by Anonymous, 2 Replies
...in the presence of HIV-1. Even without T-cell stimulation, this induced C95 expression and primed the cells for CD95- or CD3-mediated cell death. Use of the reverse transcriptase inhibitor... Read more »