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What Are The Symptoms Of Mitochondrial Toxicity

Here's a taste of what TheBody.com has to offer on this topic:
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AIDS InfoNet

Mitochondrial Toxicity

...muscle weakness in people taking AZT. It is probably the cause of "fatty liver" (hepatic steatosis) and high levels of lactic acid that can be caused by all of the nukes. Unfortunately, there is very little research on how much mitochondrial damage each ARV causes to different parts of the body. We also don't know which combinations of drugs cause the most MT. Researchers know how to measure the number of mitochondria in different cells,...
Ask the Experts

Growing concern around mitochondrial toxicity

I have been on truvada and sustiva for 9 months and for the past few weeks have been experiencing muscle aches and weakness in both legs and arms. I also have had 'muscle twitching in my leg muscles when lying still in bed. I have also been feeling...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...lactic acid levels, liver enzymes, and electrolyte/renal tests are useful for checking for significant metabolic problems due to mitochondrial toxicity. The rate of serious metabolic/mitochondrial toxicity on Truvada + Sustiva has been low (<... Read more »

mitochondrial toxicity

if it is thought that some nukes cause mitochondrial toxicities/deficiencies. can these problems interfere with the muscles ability for strenght and growth, ie. the ability to weight train?reason being is that I have had extensive fat loss on my...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...There have been some reports of impaired/slowed muscle recovery in the setting of mitochondrial toxicity. In addition, I have cared for some patients who report and have exhibited that phenomenon. It seems to be variable and is often Read more »

MITOCHONDRIAL TOXICITY

I have developed myopathy due to HIV meds. Med cocktail has been change to one with minimal toxicity. In the meantime I plan to start nucleomax,coq10,lacetyl carnitine vitb1/2/6 to minimize sxs until change of meds takes effect..Are there any foods...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...aware of any particular diet that would clearly impact the course of muscle recovery from drug related injury due to presumed mitochondrial toxicity. If any reader is aware of dietary recommendations in that setting please post! KH Read more »

What can I do to prevent mitochondrial toxicity?

Nelson: I am taking Zerit+Kaletra+Epivir and am very aafraid of this thing I keep hearing about called mitochondrial toxicity. What are the symptoms and what supplements or things can I take to prevent it? I want to get off Zerit but my doctor does...
Nelson Vergel, B.S.Ch.E., M.B.A.

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration
...inhibitors of pol gamma, although the other NARTIs exert some influence as well. To date, researchers have not studied the extent of mitochondrial damage when anti-HIV medications are combined, which is standard practice for most individuals... Read more »
Articles
The Body

The Dangers of Mitochondrial Toxicity: An Update From the 1st International Workshop on HIV & Aging

...the nucleoside analog class of antiretrovirals, which includes Retrovir (zidovudine, AZT) and Zerit (stavudine, d4T), cause mitochondrial toxicity that is associated with subcutaneous fat loss (lipoatrophy), muscle weakness (myopathy), and... Read more »
Project Inform

Mitochondrial Toxicity and Lactic Acidosis Fact Sheet

...this enzyme synergistically (where 1+1 = more than 2). At least one group of researchers claims d4T is most commonly related to mitochondrial damage in people, though others do not accept this finding. Early results from a small study show that... Read more »
Women Alive

Mitochondrial Toxicity

...gradual break-down of the mitochondria. When the mitochondria stop performing, many illnesses can arise. This is what is called mitochondrial toxicity. Some diseases related to mitochondrial dysfunction are lactic acidosis, neuropathy, muscle... Read more »
Seattle Treatment Education Project

Mitochondrial Damage

...The topic of mitochondrial damage is gaining more and more press as a potential side effect of anti-HIV medication. Simply put, the mitochondria are the "energy Read more »
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Posted by plantation84, 1 Reply
Hey Everyone, Ok where to start... I stood on a needle on holiday 2 months and 13 days ago. I went to the doctors in the country I am currently working in. (which also jails you and takes ur visa if you contract hiv or hep) They told me not to... Read more »

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Posted by Alex1, 2 Replies
SEE RED & BOYCOTT Project (RED) Auction Sothebys New York 14th February 2008 "An error can never become true however many times you repeat it. " Mahatma Gandhi (1869 - 1948). We are calling upon Bono of The (Project) Red Campaign, Damien... Read more »