What Are The Side Effects Of DdI

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Didanosine (Videx, ddI)

What Is Didanosine? ddI (Videx) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Didanosine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse transcriptase enzyme. This enzyme changes HIV's...

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DDI SIDE EFFECTS?

Four month ago my Viral Load was 22,000 and my T4 count was 420. My doctor started me on a cocktail containing the following medications:DDI 400mgs dailySustiva 600mgs dailyNelfinavir 1250mgs twice dailyD4T 1 caplet twice daily1592U89 1 capsule...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

ddI and d4T both can cause peripheral neuropathy. In some folks, they can be additive in terms of this side effect. I think ddI is a great drug and have had great results with it. You have had a great response to this regimen, but may not need all... Read more »

Side Effects from DDI and Saquinavir at thirs chage in RX in 13 years

Aloha,After 7 years of T,s in the 600 and a less than 25 VL I needed to change. T keep it short, I will remain on Kaletra and Viread. Kaletra's res was low to only 2 mutations, and Viread is not Sens which is great. The whole NNRTI class is in...

Response from Sharon Lee, M.D.

University of Kansas Medical Center

I am unsure what resistance mutations are actually present, which handicaps my answer. It is also not clear what other nucleosides you may have been on in the past. If your viral load increase was to 30,000 on treatment and you have been on Epivir,... Read more »

pls pls answer -- regimen change becasue of sever side effects from nelf ddi d4t to sustiva + ??

please please answer this question ...i am having severe lipidistrophy and atrophy changes because of my regimen (sunken cheeks, thin arms,legs and large belly, starting of hump on upper back near neck). i was on azt + 3tc for 1.5 years and then...

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital

Sorry to be slow to answer. The number of questions being posted is very high at present...too much for one person reallyI agree it sounds like a change is necessary. Tenofovir abacavir plus sustiva sounds the right combination...i generally prefer... Read more »

Effects of DDI

I have recently changed meds (today) from d4t/3tc/stocrin to DDI/3tc/stocrin. I have read the side effects etc and have been advised that DDI is safe to take with my anti seizure meds Trileptal. However, I notice that it is not advisable to take...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

To my knowledge it generally is OK to take ddI with Trileptal (also generally OK to take ddI with Dilantin or Valoproic acid). There is a possible drug interaction between Stocrine and Trileptal (could decrease Stocrine levels) and between Dilantin... Read more »

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Sustiva or DDI/hydroxurea

Posted by Anonymous, 2 Replies

I am a female recovering addict and have been clean for over ten years. I am getting real weird side effects from Sustiva and even though I started taking it at night, I feel somewhat foggy during the day. Will this end and I feel somewhat normal... Read more »

My partner was put on DDI

Posted by Anonymous, 1 Reply

Hi, My partner is HIV+ and has recently been put onto DDI and
AZT. I think, as a consequence, has become one of the most
unfriendly, annoying people in the world. Is this common, have
other people gone through this and come out the other side? I
need... Read more »

taking ddi

Posted by Anonymous, 1 Reply

Taking ddi (Videx)? Do you drink alcohol? My Dr. says I should
have no alcohol as it increases the risk of getting pancreatitis.
I continue to have one beer or one gin and tonic after work and
figure I... Read more »

wasting

Posted by Anonymous, 1 Reply

This wasting issue is certainly confusing. Ive just read an answer where the doctor said that d4t and ddi are associated with this problem, and so Ive heard from some sero+ people. Others say is because of protease inhibitors, and others say is a... Read more »

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