What Are The Side Effects Of Tipranavir

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Get the Facts

Tipranavir (Aptivus)

What Is Tipranavir? Tipranavir is a drug used as part of antiretroviral therapy (ART). It is also called Aptivus. It is manufactured by Boehringer Ingelheim. Tipranavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these scissors. Who Should Take It?...

Ask the Experts

Tipranavir

I understand that the new PI Tipranavir has been associated with some rather nasty side effects,mostly very loose stools and naussia. Are the reports over estimating the degree to which the side effects occur? Do you think we will be able to see...

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College

Tough to say. We'll have to wait for more data, but this drug will probably be used only in deep salvage and we will have to become adept at managing Tipranavir side effects in that population, as we have done before with other drugs.... Read more »

tipranavir and lipodystrophy

hello-I have heard that tipranavir is nearing approval.One of my current meds is Kaletra-I have some area's of fat redistribution. I am wondering if once approved, if tipranavir is expected to have a better profile regarding lipodystrophy side...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

I wouldn't count on it particularly since it will generally be used with ritonavir. Lexiva or Invirase or Reyataz with ritonavir may be more fat friendly than Kaletra if that is the sole issue why you would like to switch off the Kaletra. KH... Read more »

I need urgent opinion tipranavir

I will apreciate a lot your opinion. Im 25years old and my cd4 190 and vl 52,000. My doctor is offering regular treatment (lamivudine, zidovoudine, efavirenz) OR participate in a new one (tipranavir, tenofovir,lamivudine) I want to know if you have...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

It sounds like you have not been treated yet and are considering a trial for treatment-nave patients. It is not clear from your post what Tipranavir is being compared to in the study and this would be important to know. Tipranavir is a new... Read more »

Fuzeon/Tipranavir/Viread

Greetings! Back around Jan. 1st. I started a salvage treatment. Fuzeon-Tipranavir-Viread-Norvir&Trizivir. I had VERY good results Viral load going from 500,000 down to under 500 and t-cells going from 155 up to 475 as of today. Heres the thing...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

You need to fess up to your doc so he/she can interpret the situation as accurately as possible. The Norvir is needed to make the Tipranavir effective and the Trizivir (3 drugs) may be a key part of your regimen. You need to work with your HIV doc... Read more »

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Articles

FAQs About Tipranavir (Aptivus) From The Body's "Ask the Experts" Forums

Side Effects | General Treatment | Switching Treatment Side Effects High Lipid Levels From Aptivus? I have been taking Aptivus (tipranavir) as part of my drug regimen for two and a half years. My viral load is undetectable, and my CD4... Read more »

An Overview of Aptivus (Tipranavir)

tip-RAN-na-veer Brand Name: Aptivus Other Name(s): TPV Drug Class: Protease Inhibitors Tipranavir, also known as TPV or Aptivus, is a type of medicine called a protease inhibitor (PI). PIs work by blocking protease, a protein that... Read more »

Tipranavir: The First Nonpeptidic Protease Inhibitor

Introduction Recent Data BI 1182.2 BI 1182.52 Resistance Profile Drug Interactions RESIST Selected Sources Introduction Resistance to anti-HIV medications is an ongoing dilemma. A recent study in 16 European countries and... Read more »

AIDS Community Research Initiative of America

Aptivus (Tipranavir)

(In the Fall of 2003, ACRIA Update's "Drugs! Drugs! Drugs!" issue gave an overview of all the FDA-approved HIV drugs. Since that issue, one new HIV drug has been approved. We present it here for those wishing to add it to that issue, which is... Read more »

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Re: Something uplifting

Posted by SA_Intellect, 3 Replies

The link below is the response one of the doctors on The Body posted to my question. Read it. It's very positive and will hopefully add a bit of peace to some your hearts.

http://www.thebody.com/Forums/AIDS/TreatExp/Archive/Pipeline/Q173719.html ... Read more »

What should I think?

Posted by motherinlaw, 9 Replies

I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother.
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