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What Are The Side Effects Of Prezista

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AIDS InfoNet

Darunavir (Prezista)

What Is Darunavir? Darunavir is a drug used as part of antiretroviral therapy (ART). It is also called Prezista TM and used to be called TMC114. It is manufactured by Tibotec Pharmaceuticals. Darunavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissors. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these...
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Possible Prezista Side Effect

Hi,I have been taking Prezista. I've read that it can cause skin rashes. For the past month my neck and upper chest have had small bumps and have been itchy. Do you think that this is a Prezista side effect?...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Prezista(daruanvir) can cause a skin rash (more common in persons with sulfa allergy) than can be very severe and even life threatening. A month of bumps as you describe seems less likely to be a drug rash and more likely a flare up of folliculitis... Read more »


What is the side effects of Prezista/Darunavir?Any lipoatrophy or lipodystrophy?...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Good question. The best studies to evaluate lipodysrophy issues is when used in treatment naive patients comparing one regimen to one of the standard of care regimens. Increasingly, the back bone nuke regiments are abacavir or tenfovir + either 3TC... Read more »

Digestive track issues with Prezista, Truvada and Norvir

Hello Doctor,While going through my first month with NO side effects except for slightly looser stools, now, after a couple of months, it seems my stools are ALWAYS loose, not to the point of diarreah, but loose and the need to go to the bathroom...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Taking with more food, oat bran, yogurt, calcium supplement helps patients in a variable manner. Sometimes an antidiarrheal drug used judiciously can help as well. For may GI complaints will diminish over time. Sometimes the problem unmasks other... Read more »

prezista and pink eye

Hi Doctor,I am just worry about a pink eye , my left eye is bothering me and a little red (itching) is that could be a side effect of prezista? ...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello,Since drug side effects rarely, if ever, involve only one side of the body, and since pink eye in general isn't a drug side effect, no. Pink eye isn't a side effect of Prezista.BY... Read more »
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Posted by dayleth, 2 Replies


Posted by Jet, 2 Replies
Anybody have idea what are possible side effects of these 3 medications?I started taking them since couple of days ago and meennnn i have problems swallowing.At night my throat is in a mess,i cant swallow and swallowing becomes very difficult.
Are... Read more »

Prezista with out food

Posted by personpitch, 1 Reply
I've been on meds for exactly one week. So far I've had no major side effects, and am quite pleased. I'm on Truvada+Prezista+Norvir.

Today I went out to dinner and had a big meal at about 7:30. I take my meds at 9:00, and took them as scheduled. I... Read more »

Prezista - New PI designed for Resistant Virus

Posted by Survivor, 2 Replies
WASHINGTON, June 23 (Reuters) - U.S. health officials on Friday approved the use of a new HIV drug, made by Johnson & Johnson <JNJ.N>, in combination with related therapies to help treat patients who do not first improve with other... Read more »