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What Are The Pros And Cons Of D4T

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AIDSinfo

An Overview of Zerit (Stavudine, d4T)

... STAV-yoo-deen Brand Name: Zerit Other Name(s): BMY-27857, Estavudina, d4T Drug Class: Nucleoside Reverse Transcriptase Inhibitors Stavudine, also known as Zerit or d4T, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). Stavudine works by disrupting one of the early
Ask the Experts

Can I take Zerit (Stavudine, d4T) with Viread (Tenofovir).

Hi, I just had a quick question. I've been researching everywhere but couldnt find an answer, if I'm taking Zerit (Stavudine, d4T) and Sustiva (Efavirenz, Stocrin), can I take Viread (Tenofovir).Thanks so much for all your help. God bless.
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Hello and thank you for your post.While d4T (Zerit) is not routinely used with tenofovir (Viread, Truvada),nor is this a commonly used NRTI backbone to be taken with efavirenz, Read more »

GPO-Vir S30

My wife has recently been diagnosed and has a CD4 count of 380 with a VL of 30,000. The doctor (Thailand) has prescribed GPO-Vir S30 (d4t, 3TC, NVP). As I understand it this is a good regimen for reducing VL but can cause lipodystrophy due to the...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...To minimize the chances for lipodystrophy due to D4T I recommend using a lower dose of D4T (30 mg BID not 40 mg BID-I am not familiar with the dose included in GPO-Vir S30). The Read more »

Best first-line regimen with fewest side effects

My T-cells are at 260 my viral load is at 30833 copies.I have been HIV pos for 12 years, tested every six months and now I am facing therapy,my doctor would like to put e on Reyatz, Norvir and Truvada. I am very concerend about facial wasting and...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...facial wasting side effect is linked to AZT (ingredient in zidovudine, Retrovir, Combivir, and Trizivir) and Zerit (stavudine, d4T) and would not be expected with this regimen. I hope that this information helps and best of luck! Read more »

lower does d4t - side effects

sir,i started meds when my vl 264700 cd4 170 8.17% . i am on d4t 30mg+3tc+effavirenz.even though my weigth was 85 kgs my doc started me on a lower dose of d4t . this was the most prefered combination 50 wks back in india.today my vl <20 cd4 510...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...preference to to switch pro-actively before fat is lost so if tenofovir or abacavir were available and affordable I might switch from D4T to one of those agents. KH Read more »
Articles
AIDS InfoNet

Stavudine (Zerit)

...approved generic forms of stavudine for sale in the U.S. and under PEPFAR (see Fact Sheet 475 ). Stavudine is also known as d4T or didehydro-deoxythymidine. Stavudine is the most commonly used anti-HIV medication worldwide. However, in 2009, the... Read more »
AIDS InfoNet

Acute HIV Infection

...Infection? Testing for Acute HIV Infection Risk of Immune Damage Risk of Infecting Others Treating Acute HIV Infection Pros and Cons of Treating Acute HIV Infection The Bottom Line What Is Acute HIV Infection? The amount of HIV... Read more »
Test Positive Aware Network

The Feminization of an Epidemic

...sexually active while on efavirenz. Other ARVs that should be used with caution in pregnant women include didanosine [Videx] and stavudine [Zerit] together, which can lead to serious metabolic and liver conditions in women. Women with CD4... Read more »
AIDS InfoNet

Mitochondrial Toxicity

...When this happens, fewer new mitochondria are produced. The nucleoside analog reverse transcriptase inhibitors (AZT, 3TC, ddI, d4T, and abacavir) all inhibit pol gamma to some degree. MT is more likely to occur the longer you take these drugs.... Read more »
Connect With Others

BESOS CON LLAGAS AMSTURBACION CON UN POSITIVO

Posted by mexmex, 2 Replies
DISCULPE MI MOLESTIA,RESULTA QUE EN LA SEGUNDA SEMANA OCTUBRE DEL 2008 UN TRANSEXUAL QUE PRESUNTAMENTE ES VIH POSITIVO (POSTERIORMENTE ME DI CUENTA) EN ESA OCASION ME DEJE LLEVAR Y ME BESO MUY INTENSAMENTE Y ME MASTURBO A LA VEZ,LO QUE ME PREOCUPA... Read more »

INFORMACION EXCELENTE TE ACLARA EL PANORAMA

Posted by Anonymous, 1 Reply
...copias por ml de sangre. Por consiguiente, se le prepar una ingesta con dos inhibidores de proteasa, ritonavir y saquinavir, d4T, ddI e hidroxiurea. Como bien pueden imaginarse, cualquier persona que utilice estos agentes tendra efectos... Read more »

Como lidiar con mis padres sin que sea tragico?

Posted by pozargie, 5 Replies
...a mis padres... mi mama sospecha que algo anda mal, supongo que es basicamente por mis cambios de humor y asiduas visitas a profesionales medicos. Mi padre reacciona hasta casi indiferente... pero me preocupa mi madre. No quiero causarles... Read more »

Un consejo: vayan con cuidado con su salud psicol

Posted by miedoso, 1 Reply
...ventana (los tres meses): QUE OLVIDEN EL TEMA Y LA MANERA DE HACERLO ES NO DNDOLE IMPORTANCIA. A mi, no hacerlo, me gener un problema de ansiedad, que se ha generalizado a muchos otros aspectos de la vida. El miedo a que se conociese mis... Read more »