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What Are The Pros And Cons Of Crixivan

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Get the Facts
Test Positive Aware Network

Crixivan

... Common Name: indinavir sulfate Brand Name: Crixivan Class: HIV protease inhibitor (PI) Standard dose: Rarely used by itself (two 400 mg capsules every eight hours with no food or a low-fat snack). Almost always boosted with Norvir, both twice daily: 400 mg Crixivan
Ask the Experts

HAIR LOSS

Dear Dr,I was diagnosed HIV+ in 1987. Since 1995 I was on AZT and 3TC and stayed on these drugs until Jan 2001. I have experienced no side effects, but my viral load was increasing, indicating resistance.I've been on Stocrin, Norvir and Crixivan for...
John A. Bartlett, M.D.

Response from John A. Bartlett, M.D.

Duke University Medical Center
...Ian, Crixivan has been associated with hair loss and it may be responsible for your symptoms. I suggest that you review your hair loss with Read more »

Unexplained all over body hair thinning JB

I've been HIV+ since 1990. I am on 3 drug combination therapy (Indinavir-'97, Combivir-'97 & Norvir-April 00). In the last 4-6 weeks I've noticed a continuos thinning of body hair all over my body. No history of baldness or sudden hair loss in my...
John A. Bartlett, M.D.

Response from John A. Bartlett, M.D.

Duke University Medical Center
...hair, has been described for many years in persons living with HIV infection. Most recently, it has been noted in patients on Crixivan. My guess is that your hair loss is related to the Crixivan, and you and your health care provider should... Read more »

Pros & Cons From Not Taking Medications

I have recently tested HIV positive. I take no medication. What are the pros & cons of continuing without medication. Can a person within their first year of HIV encounter significant medical issues, if so, what might they be? Currently my CD4...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The current threshold for recommending starting antiretroviral therapy in the US for asymptomatic patients is a CD4 count 100,000) then consideration is more often given to start ART at higher CD4 counts. Your HIV specialist is the best person to... Read more »

Lipodystrophy

Doctor I was on crixivan+combivir for 5 years. I believe I have experienced some Lipodystrophy such as thiner face,skin and hips. Now I am on viramune+combivir for about 8 months. My body still the same. My question is if I need to go on a PI again...
John A. Bartlett, M.D.

Response from John A. Bartlett, M.D.

Duke University Medical Center
...You have asked an excellent question, and to my knowledge, the answer is not known. Your history of body changes on Crixivan do raise the concern that additional changes could occur on Kaletra. Hopefully your current regimen will maintain its... Read more »
Articles
AIDSinfo

An Overview of Crixivan (Indinavir)

... in-DIN-a-veer Brand Name: Crixivan Other Name(s): IDV, Indinavir sulfate, L-735,524, MK-639, Sulfato de indinavir Drug Class: Protease Inhibitors Indinavir Read more »
AIDS InfoNet

Indinavir (Crixivan)

...With Other Drugs? What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy (ART). It is also called Crixivan. It is manufactured by Merck & Co. Indinavir is a protease inhibitor. These drugs prevent the protease enzyme... Read more »
AIDS Project Los Angeles

When Should PIs Be Used?

...a Phase III, randomized double-blind, placebo-controlled study of Ziagen (abacavir) plus Combivir (Retrovir and Epivir) vs. Crixivan (indinavir) plus Combivir. All 562 patients enrolled in the study were antiretroviral-na├»ve. After week 16,... Read more »
The Well Project

Pharmacokinetics

...(PI) that makes the enzymes work slower. This keeps other drugs in the body longer. So if Norvir is given with another PI, like Crixivan (indinavir), it "boosts" Crixivan. The minimum concentration (Cmin) and total exposure (AUC) of Crixivan are... Read more »
Connect With Others

sustiva vs crixivan

Posted by Anonymous, 4 Replies
...everyone!! I am a 36 year old man who has been HIV + for about 12 years. I have been on long term "cocktail therapy" (Crixivan /Combivir) for almost 3 years. My CD4 counts have risen from an all time low of 65 to... Read more »

new regimine

Posted by Anonymous, 1 Reply
...700+, but viral load has recently become detectable again. I was on Epivir and Crixivan only for 3 years. Now Dr. has put me on Retonavir, Zerit, Epivir and Sequinavir. I am... Read more »

ED side effects

Posted by Anonymous
...What are the side effects when taking Crixivan and Viagra? Read more »

ED side effects?

Posted by Anonymous
...What are the side effects when taking Crixivan and Viagra? Read more »