What Are The Dangers Of Lamivudine

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Lamivudine (Epivir)

What Is Lamivudine? Lamivudine (Epivir) is a drug used as part of antiretroviral therapy (ART). It is manufactured by ViiV Healthcare. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Lamivudine is also known as 3TC. Lamivudine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse transcriptase enzyme. This enzyme changes HIV's genetic material (RNA) into the form of...

Ask the Experts

how long the treatment of lamivudine

How long is the treatment of lamivudine? My boyfriend was already taking it for 3 montns? Thank you very much.....

Response from Barbara McGovern, M.D.

Tufts University School of Medicine

The duration of therapy is not a set one - it depends on the response of the patient. The levels of virus in the blood and the outcome of hepatitis B e antigen are important levels to follow.... Read more »

Lamivudine (not) resistant after 6 months

I have been on 300mg/day of lamivudine for 6 months for treatment of Hepatitis B. It is the only medication I have ever been on for HBV or HIV. When I began the medication my HIV viral load was at very low at 190, 6 months later I am undetectable....

Response from Susan Little, M.D.

University of California San Diego

If your HIV viral load was really 190 before you started taking lamivudine, then the normal fluctiation of your viral load (off of any antiretroviral medications) would almost certainly result in many of your viral loads being undetectable. The... Read more »

lamivudine

I missed my lamivudone for three days can I continue taking them?...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hi and thanks for posting.I will assume that you are taking at least 2 other medications for the treatment of HIV in addition to the lamivudine (3TC). Missing three days of your medications is troubling, but there's really not much to do other... Read more »

Milk Thistle effectiveness and Lamivudine as monotherapy

I was diagnosed Hep-B 18 months ago and began Lamivudine monotherapy(100 mg daily) 14 months ago. I have also been taking Milk Thistle daily (200mg). What has been your experience with the effectiveness of Milk Thistle - it seems to have more...

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine

Dear BN,Many people take milk thistle in the US too. It does seem to lower enzyme levels, but does not do anything to the virus. You are right to worry about resistance with lamivudine monotherapy. It can be as high as 40% after one year. On the... Read more »

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