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What Are The Dangers Of Invirase

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Get the Facts
AIDS InfoNet

Saquinavir (Invirase)

... What Is Saquinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Saquinavir? Saquinavir, also called Invirase, is a drug used as part of antiretroviral therapy (ART). There used to be a version called Fortovase that is no longer made. Saquinavir is manufactured by Roche Laboratories. Saquinavir is a protease inhibitor. These drugs
Ask the Experts

Invirase+

Hello!I have been on medications since 1999, July - Invirase 600 mg tree times daily and Combivir 1 tablet twice daily. My viral load is still below 50 copies, my CD4 cells above 500. My doctor suggests to add Norvir to my current combination in the...
Andrew T. Pavia, M.D.

Response from Andrew T. Pavia, M.D.

University of Utah, School of Medicine
...Norvir can give better saquinavir levels and easier dosing, AND we don't know the best dosing regimens. I am surprised you are on invirase alone. Invirase, the hard gel formulation of saquinavir has been replaced by Fortavase, the soft gel,... Read more »

I recently changed from Fortovase to Norvir plus Invirase along with combivir and got a rash

Hi. I had been on a combo of Fortovase and Combivir for the last 8 years and had done extremely well. Now that Fortovase is no longer being manufactured, I was switched to a combo of Norvir/Invirase along with the Combivir. I developed a rash...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...You could be having some sort of reaction to the ritonavir (Norvir) or the higher levels of saquinavir seen when Invirase is used with Norvir (as compared to Fortavase). There is also a greater likelihood of a drug or chemical interaction between Read more »

new kaletra and invirase

I have been on a medication holiday for about 5 month and needed to go back on meds again. My doctor put me on the new Kaletra (tablets) and Invirase plus Kivexa. Eventhough I have taken both PI s before in their original version (but never...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...your MD screen for HLA B5701 status (helps predict adverse reaction to abacavir). I have had numerous patients on Kaletra + Invirase without any obvious increase in GI problems. Some patients do not tolerate particular drugs so often some... Read more »

Missed Morning Dose of Kaletra & Invirase

Hello,I apologize upfront for any duplications if this question has been asked before -?? In any case, in 1995, at age 36, I was diagnosed with HIV. My physician initially started me on AZT. Later, he changed to Viracept, Epivir and Zerit. I...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Don't worry. Your single mishap is highly unlikely to have led to any change in resistance of the virus. If you continue to be as diligent as you have been about taking your meds, I suspect you will continue to do well.Further good news is that... Read more »
Articles
Test Positive Aware Network

Invirase

... Common Name: saquinavir Brand Name: Invirase Class: HIV protease inhibitor (PI) Standard dose: Two 500 mg film-coated tablets with 100 mg Norvir two times a day Read more »
AIDSinfo

An Overview of Invirase (Saquinavir mesylate)

... sack-KWIN-uh-vihr MEH-sih-LATE --> Brand Name: Invirase Other Name(s): Ro 31-8959/003 (Saquinavir mesylate), SQV, Saquinavir mesylate, Saquinavir monomethanesulfonate (Saquinavir Read more »
U.S. Food and Drug Administration

Ongoing Safety Review of Invirase (Saquinavir) and Possible Association With Abnormal Heart Rhythms

...and Drug Administration (FDA) is reviewing clinical trial data about a potentially serious effect on the heart from the use of Invirase (saquinavir) in combination with Norvir (ritonavir). The data suggest that together the two drugs may affect... Read more »
U.S. Food and Drug Administration

Invirase (Saquinavir) Labels Now Contain Updated Risk Information on Abnormal Heart Rhythms

...and Drug Administration is notifying the public that new risk information has been added to the label of the antiviral drug Invirase (saquinavir), describing a potential change in the electrical activity of the heart when Invirase is used with... Read more »
Connect With Others

anyone taking Isentress and Invirase combination?

Posted by nevereasy
...Isentress is a relatively new therapy. My Dr just added it to my mono therapy of Invirase (boosted with Norvir). I have been undetectable for two years on the Invirase but my Tcells never get over 300. He added Isentress. Read more »

PI Monotherapy advice

Posted by logopolis, 2 Replies
Admin OptionsEdit Discussion Close Discussion Edit Your Tags Cancel Delete Discussion Hi, My partner has been asked to take part in a clinical trial - Protease Inhibitor monotherapy versus Triple Therapy. Just gathering some info before he... Read more »

26 years AIDS survior

Posted by AaronK, 3 Replies
...truvada, videx, viread, zerit, ziagen, sustiva and i dont think i took any off the other of not on the full list of NRTI. PI: Invirase, kaletra, norvir, prezista, reyataz, and vieracept. Integrase inhibitors: Isentress and the Fusion inhibitors... Read more »

Liver Function

Posted by NYRN, 1 Reply
...I'm taking viread, invirase, didanosine, zidovudine and valtrex and my latest labs indicate high on the liver screens. Has anyone had any liver issues - Read more »