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What Are Integrase Inhibitors Used For
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Ask the Experts
New Integrase inhibitor and lipodystrophy riskThere is a once a day integrase inhibitor with a non-PI booster coming up soon, isn't there? What is the integrase inhibitor called and what class does the booster belong to? Setting aside the relative newness of these drugs (and therefore the...Response from Gerald Pierone, M.D.
AIDS Research and Treatment Center of the Treasure Coast
Hello and thanks for posting. The new integrase inhibitor medication is called elvitegravir and the booster is GS 9350. The booster is one of a new class of drugs designed specifically to inhibit the CYP3A liver enzyme system. We already know that...
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Integrase InhibitorDr. Young, I am very interested to hear your thoughts on Integrase Inhibitors. -Do you think they... Read more »integrase inhibitori know that integrase inhibitor are doing very very well..the results are very impressive given the... Read more »
Articles
Comparing Two Integrase InhibitorsIt was more than a wish that integrase inhibitors became weaponry against HIV. We've waited a long time to get to this point and an even longer time to arrive at the position where we're now studying and comparing two integrase inhibitors.... Read more »Integrase Inhibitor '572 Tested Against Raltegravir-Resistant HIVGlaxoSmithKline (GSK) has licensed an anti-HIV integrase inhibitor discovered by the Shionogi Corporation in Japan. Because of these arrangements, this drug has the complex code name S/GSK1349572 and for now is increasingly referred to simply as... Read more »GSK572 Integrase Inhibitor Shines In Phase IIS/GSK1349572 -- or GSK572 for short -- is a second-generation integrase inhibitor being developed jointly by Shionogi and ViiV Healthcare. Prior research has shown that it works against HIV with some raltegravir-resistance mutations and has a high... Read more »The Rise of Integrase InhibitorsRaltegravir (Isentress) was the first integrase inhibitor to be approved for the treatment of HIV infection. This drug helps to quickly suppress production of HIV and is generally well tolerated and has few significant interactions with other drugs.... Read more »
Connect With Others
Integrase Inhibitor
Posted by Survivor
I just wanted people realize there is hope and continued very active DRUG DISCOVERY!Merck, Gilead Release Strong Findings From Clinical Trials of Experimental Integrase Inhibitor Antiretroviral Drugs Whitehouse Station, N.J.-based Merck and Foster... Read more » Today's LA Times Article - Integrase Inhibitors
Posted by Anonymous
Very hopeful! (Despite the sad title.)http://www.latimes.com/news/nationworld/nation/la-me-salvage2jan02,0,1565232,full.story?coll=la-home-headlines Read more » Entry Inhibitors
Posted by Anonymous, 1 Reply
Does anyone know anything about the new entry inhibitors? I think Pfizer and Schering both have drugs in development. Should we be hopeful?
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Fusion Inhibitor News?
Posted by Anonymous
Does anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the study for T-20(?)I went to the Trimeris site and didn't see anything new. Read more »
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