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Viral Protease Inhibitors

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Ask the Experts

Protease inhibitors and viral load

Specifically how do protease inhibitors work to decrease the about of virus (the viral load) in the serum?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
They work inside cells infected with HIV to decrease or eliminate mature, infectious viral particles from leaving the cell.MH... Read more »

Necessity to do Viral Loads before Rxing aProtease Inhibitor

Viral Load testing is very expensive, therefore a number of persons unable to pay or not in a... Read more »

cryptococcal meningitis Resistant to Protease Inhibitors

What would you advise a patient with CD4s of 8, a Viral Load over 100,000, off therapy for six... Read more »
Articles
Henry J. Kaiser Family Foundation

Protease Inhibitor Lowers Viral Loads Among HIV-Positive People With Drug Resistance, Study Finds

The protease inhibitor darunavir, sold under the brand name Prezista by Johnson & Johnson subsidiary Tibotec Pharmaceuticals , has been found to effectively decrease HIV viral loads after 48 weeks of use among people who have developed drug... Read more »
Henry J. Kaiser Family Foundation

Tibotec Experimental Protease Inhibitor Successfully Lowers Viral Loads of HIV Patients With Drug Resistance, Study Shows

A protease inhibitor produced by the Belgian pharmaceutical company Tibotec , a unit of Johnson & Johnson, has shown success treating HIV-positive people who are resistant to other medications, researchers at the 12th Conference on Retroviruses... Read more »
Henry J. Kaiser Family Foundation

Phase II Clinical Trial Shows Vertex's Experimental Protease Inhibitor Lowers Hepatitis C Viral Loads to Undetectable Levels

Cambridge, Mass.-based pharmaceutical company Vertex Pharmaceuticals on Tuesday released results of a Phase II clinical trial that showed its experimental drug VX-950 lowered hepatitis C viral loads to undetectable levels, the AP/ Houston Chronicle... Read more »
AIDS InfoNet

Protease Inhibitors in Development

Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes)... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »