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Tipranavir Dose

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AIDSinfo

An Overview of Aptivus (Tipranavir)

tip-RAN-na-veer --> Brand Name: Aptivus Other Name(s): TPV Drug Class: Protease Inhibitors Tipranavir, also known as TPV or Aptivus, is a type of medicine called a protease inhibitor (PI). PIs work by blocking protease, a protein that HIV needs to make more copies of itself. HIV/AIDS-Related Uses Tipranavir, to be coadministered with ritonavir, was approved by the FDA on June 22, 2005, for use with other antiretroviral...
Ask the Experts

High dose Kaletra revisited

What would be the clinical reason for taking Kaletra 1200mg/300mg BID? Isn't this awfully high?
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Yes, this is a high dose and would typically be recommended when attempting to overcome partial resistance to Kaletra by increasing the dose in order to achieve higher drug concentrations. Another scenario is when double boosting of PIs is being... Read more »

Planning

Doctor Young, thanks for your help. I have rather high level of drug resistance which I reported to you earlier. Treatment naive, 200 plus CD4 and 200,000 plus viral load about 2 months back. Based on reported resistance, you advised a nNRTI...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for writing back.After more careful review, it looks like there isn't a significant pharmacokinetic interaction between conventionally-dosed efavirenz (Sustiva) and tipranavir+ ritonavir. So, provided that your doctor has a reason to believe... Read more »

Governor Elect Wohl- California. The Next five drugs that might hit the market soon?

Dr. and Governor Elect Wohl- California,Well why not? I'm sure you be better than any of these idiots running for office here. But seriously, Dave can you please tell me what five drugs seem to be arousing the most curiousity and will hit the...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Thanks but I bet you are just saying that because Adrianna has bowed out.It is difficult to predict which drugs will make it all the way to FDA approval but we will probably see the following:Fosamprenavir - this is a pro-drug of the protease... Read more »

2004 dead for hiv drug approval/Norvir price hike

Dr. Gerald,After 2003 was so productive for record hiv approvals, why is 2004 so dead for hiv approvals?Ben
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
It is hard to know why drug approval seems to occur in cycles. There are very promising agents in the pipeline for HIV treatment, but dark clouds are on the horizon. Tipranavir is eagerly awaited for use in salvage therapy. This protease inhibitor... Read more »
Articles
The Body PRO

Maximum Tolerated Effective Dose of Tipranavir

Tipranavir/Ritonavir: Derivation of Doses That Achieve Effective Plasma Concentrations Above the IC50 for Multiple PI-Resistant HIV-1 Viruses (TuPeB4437) Authored by S. McCallister, V. Kohlbrenner, D. Mayers View the original abstract Scott... Read more »
AIDS InfoNet

Tipranavir (Aptivus)

What Is Tipranavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Tipranavir? Tipranavir is a drug used as part of antiretroviral therapy... Read more »
The Well Project

HIV Drug Chart/Overview

Table of Contents Introduction Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTIs) Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Integrase Inhibitors Protease Inhibitors... Read more »
Test Positive Aware Network

Aptivus

Common Name: tipranavir (TPV) Brand Name: Aptivus Class: HIV protease inhibitor (PI) Standard dose: Two 250 mg capsules with two 100 mg capsules of Norvir, both twice daily. Must be taken with Norvir. Oral solution available;... Read more »
Connect With Others

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »

Two weeks down and a life time to live

Posted by trulife, 2 Replies
Well folks...it's the end of two weeks on Atripla and so far things are going well. Side effects have been limited and are now subsiding. My biggest problem so far is swallowing the pill. I have always had trouble swallowing pills...go figure...a... Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

Skipping Doses

Posted by chrisnxs, 2 Replies
Hello Everyone, can someone please elaborate on the severity of skipping meds? My bf is positive and has been on meds for about a year. He's on my insurance and it kills the price down to a point where he can get his meds pretty easily. I discovered... Read more »