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The Role Of Rna Polymerase In Hiv

Here's a taste of what TheBody.com has to offer on this topic:
Articles
Treatment Action Group

Oral Antivirals: HCV Protease and Polymerase Inhibitors

The NS3-4A serine protease enzyme and the NS5B RNA-dependent RNA polymerase enzyme are primary targets for oral antiviral agents, since both enzymes are essential for HCV replication. Unfortunately, HCV's high replication rate -- billions of copies... Read more »
San Francisco AIDS Foundation

HIV Causes AIDS: Proof Derived from Koch's Postulates

The recent surge of publicity denying HIV's causal role in AIDS begs an examination of the relationship between a specific microorganism and a specific disease. The question is this: What scientific proof is required to establish cause and effect? ... Read more »
International Association of Physicians in AIDS Care

The Role of Alcohol and Drug Relapse Prevention in the Treatment and Prevention of HIV Disease

Although HIV disease and alcohol and drug abuse are distinct illnesses, each profoundly affects the other. Alcohol and drug abuse have been associated with high-risk sexual behavior such as unprotected sexual activity. (1-7 ) Although the... Read more »
Ask the Experts

Using Polymerase to Combat Infection?

I have been told that there aren't many t-4 receptors in the human body. If the genetic code for ~only~ the t-4 receptor could be isolated, couldn't PCR replicate the receptor? What I'm wondering is this -- couldn't infected...
Rick Stryker, M.D., M.P.H.

Response from Rick Stryker, M.D., M.P.H.

University of California Los Angeles School of Medicine
Interesting thought, that perhaps one could "mimic" the process of HIV binding to T-4 (AKA CD4+ or helper cells)and trick the virus into releasing its deadly package of instructions (RNA) harmlessly into some non-infectious state.... Read more »

Role of HIV PCR (APTIMA HIV-1 RNA QUALITATIVE ASSAY FDA APPROVED FOR DIAGNOSTIC USE)

I am a family physician and first I wanted to commend your frank and frequently humorous answers to your readers questions. The appropriate use of humor when taking care of patients humanizes us as physicians. Continue your good work.I am the...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,Medical director of an urgent care facility in Vegas??? Now that must really be an entertaining position. I love Vegas and visit frequently. I'm always amazed at the often bizarre-appearing folks I see lumbering in and out of casinos on The... Read more »

APTIMA HIV-1 RNA QUALITATIVE ASSAY (APTIMA - HIV-1 RNA QUALITATIVE ASSAY, 2010) Part 2

To the good Dr. Bob, I have submitted a donation on-line, and will submit a heftier holiday donation as well, but in the interim I was hoping you might field another inquiry from me regarding a post of mine a few weeks ago pertaining to the Aptima...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi Aptimistaken,You're going to qualify for an advanced degree in nucleic acid polymerase chain reaction laboratory analysis before long. Dude, it's time to turn off your inner scientific geek and come back to planet earth. I can't... Read more »

Testing after PEP - Peculiar concerns (HEPATITIS C AND DELAYED HIV SEROCONVERSION, 2011) (APTIMA - HIV-1 RNA QUALITATIVE ASSAY, 2011) (p24 ANTIGEN TESTING, 2011)

Dear Doctor FauscinoWith my apologies if some of the questions below seem repetitive. I hope I do not upset you. There are some matters below that are somewhat distinct and I am hopeful you can add some additional clarity and/or confirmation to....
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,No apology is necessary. I've answered so may questions in this forum over the years that greater than 99% of the questions I respond to on a daily basis I've already addressed (many multiple times). Responding to your specific... Read more »
Connect With Others

Difference between RNA-PCR and RNA-bDNA tests?

Posted by Anonymous, 1 Reply
Does anybody know the difference between RNA-PCR and RNA-bDNA tests?

Are these tests accurate? Any false negative or false positive results? Are they worth taking to evaluate early HIV infection when possible early HIV infection symptoms are present?

I... Read more »

< 400 copies of HIV RNA per 1 ml of plasma (????)

Posted by Anonymous

PCR RNA @ 28 Days...

Is this a woo-hoo ?
Read more »

Undetected HIV-1 RNA,PCR at 17 weeks

Posted by roma2010, 2 Replies
hiya all i have the results of my 17 close to 18 weeks results of a PCR RNA for HIV-1 and it was undetected testing was done by COBAS AmpliPrep (Roche Molecular systems) qualification range of this assay is 48 to 10,000.000 copies i also went to a... Read more »

PCR DNA or RNA

Posted by Anonymous, 1 Reply
Quantitative PCR RNA is the viral load test for HIV-1 only, right ?
For Qualitative PCR DNA for HIV-1 and HIV-2, the report format would be 'detectable' or 'not detectable', right ?..or/and would 'strain' of the hiv founded would be reported ?
To... Read more »