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The Effect Of Hiv On T Helper Cells And Macrophages

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Get the Facts
San Francisco AIDS Foundation

How the Immune System Fights Disease

...hundreds of different chemicals, must be coordinated for the immune system to function smoothly. The immune system can mount a variety of responses to attack specific invader organisms. One of these responses is coordinated by T-helper cells (also known as T cells, T4 cells, or CD4 cells), which act as a kind of orchestra conductor. The T-helper cells tell other cells what to do when this response is triggered. We are interested in this...
Ask the Experts

Helper T-Cells

I've read that non-progressors produce certain type of "T helper Cells" in enough quantity so as to contain the virus, while progressors produce the same kind of "T helper Cells" but not in enough quantity. Has anybody tried yet to clone these...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...cells you are referring to I believe are the CD8 cytotoxic t cells. This type of cell is the primary containment mechanism of HIV replication. The mechanism by which these cells contain replication is the subject of intense research. Infusing... Read more »

Injected helper t cells to rebuild immune system?

Sir Bobby,Real quick. What about injected helper t cells in combination with hiv medicines to prevent aids from happening? Or what about inject helper t cells as a shot during treatment iterruptions? What do you stay?Please stay well till your...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...(a T-cell growth factor), grew and expanded T-cell populations (both CD4 and CD8) outside the body, and re-infused them into HIV-positive folks. The results were mixed. These types of therapies are incredibly complex, very expensive, and... Read more »

Helper T Cell Rebound Following Chemotherapy

I recently completed a course of chemotherapy (2 cycles of Mytomycin C and 5FU) and radiation therapy (6 weeks) to treat squamous cell carcinoma. I have been HIV positive since 1985 and my CD4 levels have always been in the 500-600 range. ...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
A reduction in CD4 counts is commonly seen with chemotherapy or radiation therapy. Only time will determine whether you will get up to your pretreatment levels. It can take weeks to months to recover counts. I have seen it both ways in my practice.... Read more »

High T-Suppressor cells

hello doctor. i just got my result and it shows that i have too high corrected T-suppressor cells. what does it means? i also have low corrected T-Helper cells of 283.. what are my chances of survival.... i have no info about my viral load count...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...Your CD8 (suppressor) number is increased as a result of HIV infection. Your CD4 count is decreased as a result of HIV infection. Given where your CD4 count is currently, HIV treatment would Read more »
Articles
Seattle Treatment Education Project

The Immune System -- An Overview

...presented by the APC. The production of antibodies and the activity of CD8+ killer T cells are highly regulated by the CD4+ helper T cell subset. The CD4+ T cells provide growth factors or signals to these cells that signal them to proliferate... Read more »
The Well Project

Understanding the Immune System

...go into action. T Cells Once antigens are processed and displayed on the surface of macrophages, they can be recognized by helper T cells (also known as CD4 cells). When CD4 cells "see" the antigens displayed, they get busy and put the word out... Read more »
National Cancer Institute

Understanding Cancer Series: The Immune System

...response, while others are cytotoxic and directly contact infected cells and destroy them. Chief among the regulatory T cells are helper T cells. They are needed to activate many immune cells, including B cells and other T cells. Cytotoxic T... Read more »
Canadian AIDS Treatment Information Exchange

The Immune System

...their surfaces. CD4+ cells are T cells that have a protein called CD4 on their surface (also referred to as CD4 positive or helper T cells or T4 cells). CD4+ cells lead the attack against infections. They release chemical messengers called... Read more »
Connect With Others

Macrophage Activation Syndrome

Posted by Dgrace, 1 Reply
...My brother found out he had HIV in July of 2010, his count was under 200, He did not know he had HIV and only recently had symptoms of the disease. He started Read more »

Interferon and Hiv

Posted by ethan_hines, 2 Replies
...Why doesn't pegylated Interferon work the same way with Hiv as it does with HVB/C?. Isn't Interferon very important in fighting RNA virus infections which Hiv is one of? How does Hiv get Read more »

positive or negative?

Posted by wasek, 1 Reply
...Once HIV gets into the body, it passes instructions into T helper cells on how to make more HIV. These instructions are known as "provirus". Later on the infected T helper cell turns into a factory Read more »

Read the stories but I think I'm still +

Posted by Anonymous, 5 Replies
...know what I mean. I am worried that I got some vaginal secretions into my mouth and then into my blood stream. I dont know her hiv status but I've found out that she has let a lot of guys do this. Afterwards, I felt extremely guilty for cheating... Read more »