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Taking Hiv Drugs With Milk

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AIDS InfoNet

Silymarin (Milk Thistle)

Most of the scientific studies of silymarin were published in Europe. The Bottom Line Silymarin is an extract of the seeds of the milk thistle plant. It has been used for over 2,000 years to treat liver problems. No serious side effects or dangerous interactions have been noted. For people with HIV, especially if they have had hepatitis, silymarin might help protect the liver from damage caused by ARVs. It might also reduce stomach upset...
Ask the Experts

Milk thistle (Silymarin) and HIV meds

Im on PEP - Is milk thistle good or bad for a regime of AZT+3TC and Indinavir.. Thought taking it would help me protect my liver...thanks...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Although there has been alot of interest in the possible benefit of milk thistle in the setting of HIV or hepatitis C there is no good data suggesting that it is useful to prevent side effects of HIV meds. A 4 week course of your HIV meds usually is... Read more »

Will Milk Thistle interact with the HIV Med and safe to be taken?

Dear Dr Keith,This is Ed from Malaysia and i am currently taking Tenvir-em + Stocrin as the first line treatment.I am wondering if Milk Thistle with the following content can be taken and will it interact with the above HIV med?The Milk Thistle is...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Cannot recommend an effective dose of milk since benefit and safety in the setting of HIV infection has not been well studied. From the ACTG website there is a potential interaction between milk thistle and efavirenz that may increase the efavirenz... Read more »

Milk thistle study show drug interaction .

I did search of milk thistle on thebody site and found. CATIE A WARNING ABOUT MILK THISTLE AND DRUG ITERACTIONS. June 12, 2001says small amounts of milk thistle can slow CYP3A4 by 50 to 100. I have been takening for four years.How can I find out...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There was an article published in the journal Drug Meta Dispos (in 2000; volume 11; pp 1270-3) from a German group looking at the effect of milk thistle in liver cells in a test tube. They found that mild thistle impaired cyp 3A activity.... Read more »

Alternative Liver Detoxifiers other than Milk Thistle

I fully understand the concern about mixing Milk Thistle (sylamarin) with certian HIV meds since some of these both share the 450 cytochrome pathway in the liver for meatbolism. I have had success using phosphadytal choline (in Lectithin) and...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Thanks for your thoughtful comments. In this forum I frequently refer readers to sources of information about alternative therapies (i.e. Jon Kaiser's book Healing HIV or the website).We often have minimal drug interaction... Read more »
Connect With Others

any babies infected by breast milk?

Posted by Anonymous, 3 Replies
Would someone know how many if any babies hiv infected by breast milk?

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Anyone else taking Drug Holidays?

Posted by Anonymous, 2 Replies
Hi everyone, new to this Bulliten Board, but was wondering if anyone else has taken a drug holiday, I know most doctors DO NOT agree with doing this, but was just wondering.

Read more »

a lot of HIV virus in the milk?

Posted by aspn, 3 Replies
I bought a carton of milk 3 days ago, i drank it this morning, and i found the milk carton has a lot of blood on the carton, I am afraid , will someone intentionally given the blood in the carton and i drank it? I was afraid that there is... Read more »