Taking Crixivan When You're Hiv Positive

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An Overview of Crixivan (Indinavir)

in-DIN-a-veer Brand Name: Crixivan Other Name(s): IDV, Indinavir sulfate, L-735,524, MK-639, Sulfato de indinavir Drug Class: Protease Inhibitors Indinavir sulfate, also known as Crixivan, is a type of medicine called a protease inhibitor (PI). PIs act by blocking protease, a protein that HIV needs to make more copies of itself. Indications and Usage Indinavir was approved by the FDA on March 13, 1996, for use with other...

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crixivan causing hypertension

My son developed hypertension at age 10 from crixivan. He never took it again. I am 35 & have been taking crixivan for 10 years with short STIs. I developed hypertension 2 yrs ago. I'm wondering if Crixivan has possibly caused mine? My...

Response from Eric Daar, M.D.

UCLA School of Medicine

Thank you for your posting.In my mind it is very difficult to demonstrate with any confidence that antiretroviral therapy, including Crixivan (indinavir) cause hypertension. That said there are some studies suggesting that there may be increased... Read more »

crixivan, good or bad?

Hi,Firstly, thank you for the amazing work you all do both here and in your jobs. The world needs more people like you guys! Anyway, Ive been positive almost 3 years. I was on kaletra and combivir. I was recently hospitalized with PCP. Since...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

From what you write I am completely unclear what your doctors are thinking. If your virus is resistant to lopinavir (one of the drugs in Kaletra) chances are it will also be resistant to indinavir (Crixivan). Further, if you have other options why... Read more »

replacement for Crixivan?

I am a 41 year old black gay man (diagnosed positive in 1994) who has been on a twice a day regimen of 400 mg. Norvir, 400 mg. Crixivan, 40 mg. Zerit, and 150 mg. Epivir for several years. This combo has been very effective in maintaining an...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Wow-I am impressed you have been able to stick with that regimen!! If you have never failed an HIV regimen (meaning that your current regimen is your first and the virus has been suppressed after the first few months) then you likely have numerous... Read more »

crixivan belly and increased breast size,fed up!

For 2 years I have had to tolerate my pregnant looking stomach, that I can't stand to look at anymore. My breast went from a 36B to a 38DD, now this is to much.My doctor said that it was benifial for me to continue PI's and so I did for a...

Response from Alvan Fisher, M.D.

Brown University School of Medicine

Let me get this straight...your counts got worse on treatment, better when you stopped? Your fat accumulation also got worse after stopping treatment?? Some people believe that these problems are related to HIV with or without treatment...though... Read more »

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