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Sustiva And Epzicom Combination

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AIDS InfoNet

Epzicom/Kivexa (Abacavir + Lamivudine)

What Is Epzicom? Epzicom is a pill that contains two drugs used to fight HIV: abacavir (Ziagen) and Epivir (lamivudine, 3TC). Epzicom is manufactured by ViiV Healthcare. Outside the US, it is called Kivexa. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). The drugs in Epzicom are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase enzyme. This enzyme...
Ask the Experts

epzicom/sustiva or combivir/sustiva

Hi Dr. Young! I am 37, have been HIV positive for about 2 years and had continuously drop in cd4 cells, now 345 and my doctor wants me to start treatment. He offers 2 possible treatment epzicom(here kivexa)/sustiva(here stocrin) or combivir/sustiva...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thank you for your post.First off, I'd agree that if your willing and able to be adherent to medications, with a CD4 count around 350, it would be best to consider treatment.Both Epzicom (Kivexa) and Combivir are... Read more »

Sustiva+Epzicom in one pill?

Hi Dr. DeJesus, I currently switched from Atripla to Sustiva+Epzicom due to increasing liver/kidney function. I notice while reading your profile that you have been in close contact with the drug companies. Is there any future plans that you know...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

It is very unlikely that Sustiva and Epzicom will ever be combined into a single tablet. There are a lot of logistic reasons why that would not happen, and probably they are not worth trying to overcome to bring the pill count down from 2 to 1. I... Read more »

Sustiva and Epzicom vs. Truvada

Hi...This is less a question than what I suppose may come off as a testimonial. I began treatment last month with a viral load of 330k and a cd4 of 230. My regimen consisted of once-daily Sustiva & the new once-daily epzicom. I developed a...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your comments.Both of the new fixed-dose combination pills, Epzicom and Truvada have been shown to be very effective and potent in combination with efavirenz (Sustiva). As you have experienced, a percentage of persons who take Epzicom... Read more »

Changing from Epzicom+Prezista+Norvir to Combivir+Sustiva

Hi, doctor.It's me again. I previously posted here about my partner being prescribed with Atripla, Trizivir and Viread by his primary doctor when he was admitted to the hospital. After he was discharged, he was finally able to visit an HIV...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and good to hear back from you.Good to hear that you're partner is now on a more conventional regimen. The current regimen is one of the current US Department of Health and Human Service Guideline "alternate" ranked ones- and... Read more »
Connect With Others

New combined Truvada/Sustiva combination

Posted by Anonymous, 3 Replies
Hi.
Just wondered if anybody knew as to when the above co-formulated combo will be available? I s it this year?
I am starting with Truvada + Sustiva, but as I not keen on taking tablets anyway, I would rather take just 1 tablet instead of 2.
Thank you Read more »

Sustiva + Truvada combination

Posted by richwales, 6 Replies
Im a 26 y/o male living in UK whos been on sustiva and truvada for 4 months now my Cd4 and viral load are doing great (gone from 14% 245 to 19% 472, and 18,200 to undectable) just finding the side affects of sustiva really can be hard to cope with,... Read more »

New to Epzicom...Help with side-effects

Posted by Keoki, 1 Reply
Anybody out there on Intellence and Epzicom? I'm new to Epzicom. I had to stop Truvada, because of kidney function issues. I'm having a bit of a hard time adjusting to the Epzicom...nausea, lethargy, and just not "feeling right." Any information... Read more »

Abacavir - Hypersensitivity - EPZICOM

Posted by Survivor, 2 Replies
David, I read your Email and brought the PDF forward. Dr. Ben was very watchful when I initially got started and had follow up calls to me regarding any problems if in deed I was blinded on the Abacavir. Either I am on it and am fine or I am not... Read more »