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Stavudine Drug

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AIDSinfo

An Overview of Zerit (Stavudine, d4T)

... STAV-yoo-deen Brand Name: Zerit Other Name(s): BMY-27857, Estavudina, d4T Drug Class: Nucleoside Reverse Transcriptase Inhibitors Stavudine, also known as Zerit or d4T, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). Stavudine works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal
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Can I take Zerit (Stavudine, d4T) with Viread (Tenofovir).

Hi, I just had a quick question. I've been researching everywhere but couldnt find an answer, if I'm taking Zerit (Stavudine, d4T) and Sustiva (Efavirenz, Stocrin), can I take Viread (Tenofovir).Thanks so much for all your help. God bless.
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Hello and thank you for your post.While d4T (Zerit) is not routinely used with tenofovir (Viread, Truvada),nor is this a commonly used NRTI backbone to be taken with efavirenz, Read more »

d4t to AZT

I have suffered severe lipoathrophy, i tested positive in june 2005.iwas immediately placed on Stavudine, neviripine and lamuvidine. i did quite well and later started noticing that i lost muscles and fat on my thighs, buttocks, arms, and legs and...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...There has been little published about what happens to peripheral fat when D4T is switched to AZT. AZT generally has a milder effect on peripheral fat so some patients may note a slow increase after the Read more »

Concerns about long time Stavudine use in a child

My son was diagnosed with AIDS in 1/20/04. As of 6/2004, he has been on a regimen of Stavudine, Lamuvidine and Kaletra. I am concerned about the long term effects of Stavudine. Are there better combinations? Are we going to be sorry that he stays...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...In adults there has been a unmistakable shift away from using stavudine (Zerit) towards tenofovir (Viread). One of the main reasons for this change is that Viread has a better side effect profile Read more »

D4T & Viramune?

I am building a resistance to combivar. I have been on AZT since it first came out in the late 80's. Mr Dr. is suggesting a switch to D4T and Viramune. I am concerned about the lipodystrophy factors with D4t. Any other combinations you would...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
...Well, it is not settled that stavudine (d4T) is the responsible agent for lipodystrophy, in fact studies clearly show that it can happen with ALL of the other antiretroviral Read more »
Articles
AIDS InfoNet

Stavudine (Zerit)

... What Is Stavudine? Who Should Take Stavudine? What About Drug Resistance? How Is Stavudine Taken? What Are the Side Effects? How Does Read more »
Test Positive Aware Network

La Guía Annual de Medicamentos para el VIH: Zerit (Stavudine, d4T)

...   Nombre de Marca: Zerit Nombre Común: stavudine o d4T Clase: nucleósido análogo (también llamado inhibidor de la transcriptasa reversa del nucleósido, NRTI, siglas en Read more »
The Body PRO

Abstract No. 420: A Phase I Study of Hydroxyurea in HIV-Infected Children Receiving Didanosine (ddI) and/or Stavudine (d4T)

...Medicine, evaluated the safety, antiviral and immunologic effects, and pharmacokinetics of hydroxyurea, given with ddI and/or d4T to symptomatic HIV-infected children. It is among the first to look at the use of HU in children. The children... Read more »
International Association of Physicians in AIDS Care

A Note to Physicians: Important Information on the Combination of Zidovudine (ZDV) and Stavudine (d4T) in ZDV-experienced HIV-Infected Patients

...weeks. An interim analysis of this study revealed that the average CD4+ T cell count in patients taking the combination of d4T and ZDV decreased from the time they entered the study. NIAID recommends that physicians closely monitor the CD4+ T... Read more »
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Just started ARV - Insurance, Drug costs, expenses

Posted by ajhope, 1 Reply
...29,000 - I started ARV 2 weeks ago with the following regiments: Nevirapine 200 mg - once a day Lamivudine 150 mg - twice a day Stavudine 30 mg - twice a day After another blood test to make sure that my liver and kidney functions are OK which... Read more »

50% of HIV+ Develop Neurocognitive Impairment

Posted by ScotCharles, 3 Replies
...to the kinds of specific treatments they received, such as a type of drug called the "D" drugs [didanosine (ddI, Videx) and stavudine (d4T, Zerit)]. Coming back to the brain involvement, we also tried to look at [whether there are] some things... Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »