Starting Treatment With Very Low Cd4

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Ask the Experts

DOES LOW CD4 AT START OF TREATMENT = GREATER LIKLIHOOD OF TREATMENT FAILURE?

Hi BenI recently found this study that suggests starting treatment at lower CD4 counts causes a MUCH greater risk of treatment failure. I started at around 80 T cells, with a boosted protease regimin, and have been undetectable for a year with no...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello Michael and thanks for your post.The study that you've cited is one from our HOPS study colleagues- this study doesn't conclude that persons with low CD4s are more likely to have treatment failure, rather, it says that if someone... Read more »

Low CD4, OK CD4 Count, Start Treatment?

Without going into a lot of treatment history, I have been positive since October 1999. I've... Read more »

Response from Gerald Pierone, M.D. »

Low CD4 count when starting treatment

Recently diagnosed in May 2009 as part of routine bloodwork. CD4 count of only 78 and VL of... Read more »

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C. »

Go to Ask the Experts »

Articles

Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system.... Read more »

HIV-Infected Patients Who Have the ApoE4 Allele Are More Vulnerable to the Effects of Low CD4 Counts

My name is Kalpana Kallianpur and I'm from the University of Hawaii, the Clinical AIDS Research Group there. My coauthors on this project are Aaron McMurtray, Victor Valcour, Bruce Shiramizu and Cecilia Shikuma. This work was an offshoot of a larger... Read more »

Maternal HAART Use During Breastfeeding Can Significantly Reduce Mother-to-Child Transmission Among Women With Low CD4+ Cell Counts, Study Finds

There's nothing like hearing the results of studies directly from those who actually conducted the research. In this study summary, Taha Taha, M.D., Ph.D., of the Johns Hopkins University Bloomberg School of Public Health discusses the results of a... Read more »

No Difference in AIDS-Free Survival in Children Starting ART With a CD4% Between 15%-24% Compared to Deferring Until Less Than 15% in the PREDICT Trial

Information to guide initiation of treatment in children older than one year of age is scarce. Results from the PREDICT trial -- presented as late breakers at both IAS 2011 and the preceding pediatric workshop -- found that deferring ART until CD4... Read more »

Connect With Others

treatment starting at higher cd4

Posted by alive2, 1 Reply

now that people are being told to start medication at a higher cd 4 number does this pose a bit of apprehencion? will the first prescribed medications last longer? is it a ploy by big pharmacutical companies?
to me i worry when the cdc or reports... Read more »

Help! BF has low CD4 and high VL

Posted by LoveofMyLife, 2 Replies

Hi everyone. I'm negative. My bf has been positive for 21 years. He has been non-compliant with his meds off and on over the years. This week, we found out that his CD4 is 65 and VL is 80,000. His doc (an HIV Specialist) is doing the resistance... Read more »

Negative but with a very low CD4 and CD4/CD8

Posted by tobeabetterman, 1 Reply

Hi everyone , sorry to bother again .
I was once told by dear kicker and riverprincess that my 3 months result is conclusive , thank you very much with my best wishes , and I'm sorry I have bother you again .
Some new situation make me nervous again .... Read more »

cd4 at 35 and viral load 521 advice please!!!!

Posted by poliwog, 5 Replies

I just got back my labs. I started on Combivir and Kaletra 6 months ago. My viral load was over 100K and mt cd4 at 90. Afer 6 months my VL wentr way down but my cd4 count is 35. I was given two meds to fight any possible secondary infections and... Read more »

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