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Side Effects Of Lexiva Vs Kaletra

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AIDS InfoNet

Fosamprenavir (Telzir, Lexiva)

What Is Fosamprenavir? Fosamprenavir is a drug used for antiretroviral therapy (ART). It is also called Lexiva TM . In some countries, it is called Telzir. It is manufactured by ViiV Healthcare. Fosamprenavir is a pro-drug. The drug you swallow is not active against HIV. It breaks down in the body to produce the active form, which is the drug amprenavir (see Fact Sheet 445 ). Fosamprenavir is a protease inhibitor. These drugs prevent the...
Ask the Experts

Lexiva & Kaletra

I was recently prescribed Lexiva & Kaletra and I was wondering were there any more testings done to see how effect these drugs are together. What are your thoughts on these drugs? Also is there anything out to reverse, reduce or prevent...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Lexiva can lower lopinavir levels so checking plasma levels is recommended due to the unpredicaable but often negative interaction between those protease inhibitors. KH... Read more »

Switching to Lexiva/Telzir, Norvir and Truvada

Two years ago I've started taking Kaletra and Combivir. It works very fine for me, nearly without any side effects, my virus load is undetectable and my CD4-count raised from 150 up to 430. Unfortunately my cholesterol levels are relatively...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post and kind words.With the arrivals of atazanavir (Reyataz) and fosamprenavir (Lexiva, Telzir), we're seeing a resurgence in the use of first-line protease inhibitors.The proposed regimen of fosamprenavir/ritonavir with... Read more »

Clinical Trial for Lexiva

My doctor asked me to consider taking part in a clinical study. Currently I am on Kaletra and Combivir. I have been on this regime for a little over a year and have done amazingly well. When I started, my T-cells were only 17 and my viral load...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post and interest in participation in clinical studies.In general terms, it's usually safe to switch from one drug to another (within the same class), provided that your viral loads are controlled. I don't usually go... Read more »

Switch from Kaletra to Lexiva?

Dear Dr. Henry:I appreciate all the information you have provided in the past. In my last question, I asked you about switching regimens, i.e., Kaletra to Lexiva with boosted Norvir, and you answered that once a patient goes below 50 for viral load...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Usually you could switch back to the Kaletra if GI symptoms don't improve presuming the viral level is still suppressed. You might consider adding FTC with the Viread (Truvada) or 3TC and abacavir (Epzicom) as the NRTI backbone. Boosted... Read more »
Connect With Others

Insurance Help

Posted by Anonymous, 2 Replies
Hi, everyone!

I am one of those people across the country who have recently been booted from my state's ADAP. I have no insurance benefits. I am trying to get on the access programs for meds, but really need something to help with doctor... Read more »

Abbott pharmaceuticals price gouging protease inh

Posted by BabyPeanut
Editorial, The Center for AIDS (12/15/03)

In a move that startled healthcare professionals and community members alike, Abbott pharmaceuticals announced a price increase of almost 500% for its protease inhibitor ritonavir (Norvir). Norvir is widely... Read more »

eric,i need your thoughts..,or fran or bear

Posted by alivehoping, 2 Replies
i just came back from the doc yesterday and my numbers were going back up slightly not drastic but slightly enough to the point my doc wants to put me on a different regime of meds,take 1 and get a different 1. c4-400,vl 125,although it seems low... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother.
My son and daughter-in-law seem not to... Read more »

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