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Side Effects Of Fusion Inhibitors

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Get the Facts
AIDS InfoNet

Fusion and Attachment Inhibitors

...CD4 receptor. It is a genetically engineered drug, a "monoclonal antibody." It is being studied as an intravenous infusion every two or four weeks. It is administered along with antiretroviral medications. No significant side effects have shown up yet. It is in Phase II trials. INCB 9471 by Incyte Corporation has successfully completed Phase II trials in healthy volunteers. It has shown very good tolerability. However, Incyte will not...
Ask the Experts

side effects

...I was curious if there are any side effects of fusion inhibitors? Also, how do they exactly work, do they kill the viral cell before it enters the cd4 cell or does it just prevent it from entering?Thanks.
Don Kurtyka, ARNP

Response from Don Kurtyka, ARNP

University of South Florida School of Medicine
...Like any medication, there are potential side effects associated with Fuzeon and the other entry inhibitors under development. You may find the following websites helpful for a detailed Read more »

Fusion inhibitors and clinical trials.

I have recently reached the point where I need to start taking anti-HIV medications and I am seeking your advice on how to proceed.Our local AIDS Clinical Trials Unit needs people who are treatment-naive for a study involving fusion inhibitors in...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...I think that your primary ID doctor is correct. A simple regimen would probably work as well with fewer side effects. Fusion inhibitors require daily injections and are no walk in the park. If you do decide to participate in this trial you should Read more »

The beginning of something new?

Hi Dr. HenryThe way I see it is that 3tc (epivir) has virtually no side effects. Now, with fuzeon (fusion inhibitors) there are no reported side effects of toxicity either (just irritation at site of shot). Is this the beginning of something new? ...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...3TC does have some side effect but it is generally well tolerated. T-20 is expensive and has side effects in almost every patient (injection site reactions) due to the fact that it is injected subcutaneously twice a day. Regimens Read more »

Fusion Inhibitors

Can you shed any light on what, if any, of the preliminary reports on fusion inhibitors may include as far as side effects? I guess I am assuming they have done some human trials??
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...T-20 = Fuzeon is the only fusion inhibitor soon to be more widely available. Since it acts outside of cells (blocking fusion) its toxicity would be expected Read more »
Articles
AIDSinfo

An Overview of Fuzeon (Enfuvirtide, T-20)

...hemophilia or other blood clotting disorders may have a higher risk of postinjection bleeding after enfuvirtide use. Possible Side Effects Along with its desired effects, enfuvirtide can cause some unwanted effects. The most common side... Read more »
Test Positive Aware Network

Fuzeon

...Pharmaceuticals and Trimeris, www.rocheusa.com , www.trimeris.com , www.fuzeon.com , 1 (877) 4-FUZEON (438-9366) Potential side effects and toxicity: The most common are Injection Site Reactions (ISRs), which occur in virtually all... Read more »
The Body

Fuzeon: A Review of the First Entry Inhibitor

...Class of HIV Medications How Does Fuzeon Work? What We Know About Fuzeon Who Most Benefits From Fuzeon Fuzeon's Side Effects Conclusion: Fuzeon's Role in Treatment Ten Tips on Injecting Fuzeon Learn More About Fuzeon Glossary Read more »
AIDS InfoNet

Enfuvirtide (Fuzeon)

... What Is Enfuvirtide? Who Should Take It? What About Drug Resistance? How Is Enfuvirtide Taken? What Are The Side Effects? How Does It React With Other Drugs? The Bottom Line What Is Enfuvirtide? Enfuvirtide, also called... Read more »
Connect With Others

26 years AIDS survior

Posted by AaronK, 3 Replies
...I had AIDS for many years now and was the lucky one's to surive... the clinical studies.... long term side effects... and the worst isolation. I'm 26 years old and i was dianosed in 1988 when i was five years old. My parents didn't know why Read more »

information

Posted by Anonymous, 1 Reply
...characteristics * Whether they were infected with a less aggressive strain of the virus * If their genes may protect them from the effects of HIV Scientists hope that understanding the body's natural method of controlling infection may... Read more »

30 months ?

Posted by Anonymous, 1 Reply
...Drug Resistance and Staying Undetectable Fatigue and Anemia Fusion Inhibitors Hepatitis and HIV Coinfection Managing Side Effects of HIV Treatment Mental Health and HIV Mixed-HIV-Status Couples Safe Sex and HIV Prevention Tratamientos (En... Read more »

anything is possible

Posted by Anonymous, 2 Replies
...Experienced HIVers Choosing Your Meds Drug Resistance and Staying Undetectable Fatigue and Anemia Fusion Inhibitors Managing Side Effects of HIV Treatment Mental Health and HIV Mixed-HIV-Status Couples Safe Sex and HIV Prevention ... Read more »