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Side Effects Of Epzicom

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AIDS InfoNet

Epzicom/Kivexa (Abacavir + Lamivudine)

What Is Epzicom? Epzicom is a pill that contains two drugs used to fight HIV: abacavir (Ziagen) and Epivir (lamivudine, 3TC). Epzicom is manufactured by ViiV Healthcare. Outside the US, it is called Kivexa. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). The drugs in Epzicom are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase enzyme. This enzyme...
Ask the Experts

Kaletra / Epzicom - Would like holiday from Epzicom

My CD4 hovers around 400. Viral load undetectable for three years. Take Kaletra and Epzicom, no other medications. Experiencing some fatigue for a couple of years now. I know one common side effect of Epzicom can be fatigue. Would like to take a...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Fatigue is not that common with Epzicom compared to other drugs and is common in general population so hard to pin down if Epzicom is primary cause. Switch to alterantive drug (ie Truvada or raltegravir) with observation for several months to track... Read more »

longtime side effects of Epzicom - correction of previous email

instead. The mistake is in capital letters, and corrected here.Please help me with any knowledge you have so far on the long term side effects of Epzicom. I was on Combivir and Viramune from the beginning of year 2003 to 2006. I tolerated the drugs...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Epzicom usually compares favorably to Truvada when it comes to fat loss from face and risk (low but present) for peripheral neuropathy. So though the Epzicom may be a factor in the facial fat loss and leg complaints I am not confident that a switch... Read more »

Worried about Epzicom side effects

affect my kidneys and then i was switched to Epzicom to take it's place in 2006. but i'm concerned about the Cardio side effects of epzicom & it doesn't sit well with me that this med can cause a fatal allergic reaction at any...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi Jay,I, too, tend to shy away from Epzicom if there are other equally good or, in many cases, better options from which to choose. Regarding your best options, that would depend on your resistance profile, potential drug-drug interactions with... Read more »

Epzicom or Truvada and side effects

Hi Doctor, thank you for your support of this site.I am considering commencing HIV treatment at this time as recommended by my doctor. My choice is either Truvada or Epzicom combined with Sustiva.From what we now know at this time, in your opinion...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for posting.Tenofovir/FTC (TRUVADA) and abacavir/lamviduine (EPZICOM, KIVEXA) are the most widely prescribed NRTI combinations in North America and Europe. Both are generally very well tolerated and effective, though there are... Read more »
Connect With Others

New to Epzicom...Help with side-effects

Posted by Keoki, 1 Reply
Anybody out there on Intellence and Epzicom? I'm new to Epzicom. I had to stop Truvada, because of kidney function issues. I'm having a bit of a hard time adjusting to the Epzicom...nausea, lethargy, and just not "feeling right." Any information... Read more »

Epzicom + Reyataz?

Posted by Anonymous, 1 Reply
Hi.
I have just been diagnosed with a CD4 count of 11, and a viral load of 820,000.
I may start teatment with Epzicom + Reyataz and I wanted to know if anybody else had started with this regimen, or is currently on it, and what they thought of it?
Thank... Read more »

Reyataz/Norvir/Truvada/Epzicom...morning or night?

Posted by Anonymous, 3 Replies
I'm starting in a study, and I just got my meds today. I'll be on Reyataz boosted with Norvir, and either Epzicom or Truvada (I won't know which).

Does anyone know if there are any advantages to taking these meds in the morning as opposed to the... Read more »

Abacavir - Hypersensitivity - EPZICOM

Posted by Survivor, 2 Replies
David, I read your Email and brought the PDF forward. Dr. Ben was very watchful when I initially got started and had follow up calls to me regarding any problems if in deed I was blinded on the Abacavir. Either I am on it and am fine or I am not... Read more »

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