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Should I Take D4T If I Have Hiv

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Get the Facts
AIDSinfo

An Overview of Zerit (Stavudine, d4T)

...Nucleoside Reverse Transcriptase Inhibitors Stavudine, also known as Zerit or d4T, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). Stavudine works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal reverse transcription, HIV's reverse transcriptase enzyme (a type of protein) converts HIV's RNA -- a single strand of genetic information -- into DNA -- a...
Ask the Experts

switching from d4t to AZT

Dear Doctor: I am Kanta from a small state of India called Manipur. I am on ART since june 2004 with a regimen d4t, 3TC, NVP and was continue till july 2009. Due to having a problem of fat loss now I substitute d4T with AZT under doctor...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...loss; AZT is associated with much less (though still) some fat loss. It should be stated that lipoatrophy risk isn't all just HIV medications (such as d4T or AZT), but also associated with having more advanced HIV disease or lower initial CD4... Read more »

Is it right to initial ART by TDF

The first line drug includes NUKES of AZT D4T TDF ABC. Once HIV develop resistence to AZT D4T ,TDF can still supress HIV.I am in Asia of limited resource.In the case of AZT D4T TDF options,is it approprite for me to start navie ART by TDF? one...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...Yes. Starting HIV treatment with TDF (preferably with FTC or 3TC), in conjunction with an NNRTI (efavirenz or nevirapine) or Protease inhibitor Read more »

help

Dear SirI am leaving in one poor country at the momentMy CD 4 are378 my medication is sustiva, lamivudin plus stavudine, for two year, I been advise from some doctor this type of medication is not susitable I will toxic, tyhis my question from two...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...on your current drug regimen. If you are having any D4T toxicity AZT can often be successfully substituted for the D4T. Your HIV doc is the best person to assess what your best option is. KH Read more »

Nucleomaxx !!!

Hi, I want to start take nucleomaxx, as i don't know what else i can try that i didn't. i used to take zerit +videx for a long time and before crixcivan and today kaletra+videx+viread, but my legs and this whole lipo thing, i just can't take it any...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...or women. NucleomaxX (uridine sachets) is under study for the treatment of thymidine drugs (AZT or D4T) related fat loss in HIV+ persons. Data is still limited and it is unclear whether uridine would benefit patients no longer taking AZT or D4T.... Read more »
Articles
International Association of Physicians in AIDS Care

A Note to Physicians: Important Information on the Combination of Zidovudine (ZDV) and Stavudine (d4T) in ZDV-experienced HIV-Infected Patients

...cell counts of patients taking this combination. Study Description and Results The study, ACTG 290, is being conducted by the AIDS Clinical Trials Group (ACTG), a research network supported by the National Institute of Allergy and Infectious... Read more »
amfAR, The Foundation for AIDS Research

Studies Find D4T Plus 3TC Effective Against HIV

...Opportunistic Infections show that the previously untested combination of d4T (stavudine) plus 3TC (lamivudine) is effective against HIV. One study demonstrated that d4T plus 3TC was effective as initial therapy, but less effective if used after... Read more »
The Body PRO

Abstract No. 398: Treatment with d4T + ddI + Nelfinavir + Hydroxyurea for Early or Recent Primary HIV Infection

...study designed to assess the efficacy of a four-drug combination -- ddI/d4T/nelfinavir/hydroxyurea -- for patients with "early" HIV infection (defined as asymptomatic patients with a T-cell, or CD4, count above 500) or for recent HIV... Read more »
The Body PRO

Session 84, Abstract 664: Therapy with d4T plus 3TC Produces Sustained Undetectable Levels of Plasma HIV RNA in Patients Treated with Reverse Transcriptase (RT) Inhibitors for 10 Years

...is also worth repeating: a standardized approach to antiretroviral therapy is not necessarily appropriate for all people with HIV disease. Read more »
Connect With Others

50% of HIV+ Develop Neurocognitive Impairment

Posted by ScotCharles, 3 Replies
...to the kinds of specific treatments they received, such as a type of drug called the "D" drugs [didanosine (ddI, Videx) and stavudine (d4T, Zerit)]. Coming back to the brain involvement, we also tried to look at [whether there are] some things... Read more »

HIV / AIDS DOCS

Posted by Survivor, 1 Reply
...What do HIV/AIDS Doc's do, when they are not seeing you? http://www.thebody.com/thebody/ukraine.html Ben Young, M.D. In Ukraine, Clinicians Read more »

What is longest period of time HIV+ without...

Posted by Anonymous, 5 Replies
......progression to AIDS? Read more »

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »