Should I Take D4T If I Have Hiv

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An Overview of Zerit (Stavudine, d4T)

STAV-yoo-deen Brand Name: Zerit Other Name(s): BMY-27857, Estavudina, d4T Drug Class: Nucleoside Reverse Transcriptase Inhibitors Stavudine, also known as Zerit or d4T, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). Stavudine works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal reverse transcription, HIV's reverse transcriptase...

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d4t=pain

HIV+ for 20 years. d4t (zerit) is causing much painful neuropathy in hands/feet and a non-erectile penis. Already quit AZT and Crixivan.I am on abacavir+effavirenz+d4t+3tc. VRL:2000, CD8:350.Want to quit d4t but cannot find a substitute. peter...

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College

I'm not completely sure that all of your problems are related to Zerit and you should be evaluated to make sure that other conditions are not also contributing to your problems. If you and your doctor are convinced its the Zerit (d4T,... Read more »

Switching from 3TC &D4T to Combivir

I'm HIV+ sinse 1994. Three years on ART: 3TC, D4T and Efavirens. I have good response and no side effects except lipodistrophy on my face. It is only beggining stage but I know that it will develop further.In this case My doctor suggest to...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Often a switch from Combivir (AZT + 3TC) to either Truvada (tenofovir + FTC) or Epzicom (abacavir + 3TC) may slow down and possibly reverse loss of fat. The fat recovery may be slow and doesn't always occur. KH... Read more »

Ribavirin and AZT/D4T

Hello Doctor,I heard that Ribavirin cancels out AZT and also D4T. The studies to this topic are all "in vitro". What really happens in case you take a HIV-Combo with AZT or D4T and INF+Riba? In an small study there where no negative...

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine

There have several small lab studies suggesting that ribavirin might compete for phosphorylation with AZT and D4T. At our site, at Johns Hopkins, in France and Spain, we now have data on over 100 people treated with ribavirin and despite taking AZT... Read more »

Alternatives to d4T to prevent facial wasting?

I was recently diagnosed with HIV, and am starting combination therapy. I am very concerned about facial wasting. d4T was mentioned as a part of the proposed combination therapy, but I know it is considered as a possible contributor to facial...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

The direct role of D4T regarding facial wasting is still under study. There usually is not much of a problem for the first several years one is on therapy (even with D4T). If a problem develops early then one can switch off a drug(s) that could be... Read more »

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pregnancy and HIV

Posted by footeard, 1 Reply

Hi, I have been positive since 1987 and my husband is negative. I am 30 years old. We will be trying to concieve and have a baby in July. I am currently on D4T, Viramune and DDI. I was on AZT monotherapy from 92-94 at 300 mg a day so likely am... Read more »

HIV medicines

Posted by Anonymous

Do you need ANY HIV related drug or any Opportunistic Infection medication, such as: Zerit (d4T), AZT, Abacavir, ddI, ddC, Crixivan, Fortovase, Saquanavir, Viracept, Virammune, Diflucan, any protease inhibitor available at the pharmacy? Do you need... Read more »

i am an hiv+...

Posted by Anonymous

My name is Russell, I am an Hiv positive who was diagnosed 9
years ago.I work out very regularily,weights 3-4 times a week and
cardio 3-5 times a week. I am currently on d4T and ddI and
crixivan, and am experiencing no major side effects.I am... Read more »

i am an hiv male living in Sydney...

Posted by Anonymous

Iam a HIV positive male living in Sydney, Australia. Ive been HIV
positive for 13 years, have seen all of my friends die during the
80's. I dont know why I have been spared their fate. My health
did start declining during 1994, although I have not... Read more »

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