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Should I Take Delavirdine

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Get the Facts
AIDSinfo

An Overview of Rescriptor (Delavirdine)

... de-la-VIR-deen --> Brand Name: Rescriptor Other Name(s): 136817-59-9, DLV, Delavirdine mesylate, Mesilato de delavirdina,U-90152S Drug Class: Non-nucleoside Reverse Transcriptase Inhibitors Delavirdine, also known as Rescriptor, is a type of medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Ask the Experts

Worried about delavirdine

I recently started therapy for the first time after being diagnosed with HIV 2 years ago. My doctor prescribed Combivir and abacavir 2 weeks ago. I have been taking this combination with no real problems. Just yesterday, my doctor prescribed...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...Well it is unclear what motivated the decision to pick delavirdine in preference to the others. You do hear more about the others since the data we have have led us to be more confident in them. Read more »

Delavirdine interactions with Indinavir and other antiretrovirals.

Hi Dr. Cohen!Bob Frascino spoke to a group of us in Monterey, CA last week and began for the first time to explain why I have remained undetectable for so long(4+ years) on the same five drug regimen even though my dosing schedule was not precise. ...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...Yup. Very clear. Hope the answer is equally lucid.Yes -- delavirdine (for simplicity I'll abbreviate it DLV) does have similar effects on the p450 system as does ritonavir. Not as potent but similar. Read more »

Agenerase Dose w/ Delavirdine & Abacavir

Dear Dr. Cohen,Having been on nearly every drug available for the past 11 of my 42 years, my most recent geno and phenotypes show that my least resistance is to the drug combo of delavirdine/agenerase/abacavir. I had been on AMP/ABV/EFV since my...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...your case. Since the recent lesson of "boosting" levels of a PI such as amprenavir with another antiviral such as ritonavir or delavirdine is that there is a level of drug predicted to be active given the degree of resistance that HIV has... Read more »

delaviridine,viread,kaletra

I was wondering whether the combo delaviridine, viread and kaletra is potent and with less side-effects than some of the other hiv meds. What should I watch out for if I go on this combo. I am switching from fosamprenavir to delaviridine as fos...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
...This is an unusual regimen since delavirdine (Rescriptor) is rarely used anymore. It should be a very potent regimen, but Kaletra and delavirdine are not known for a low Read more »
Articles
AIDS InfoNet

Delavirdine (Rescriptor)

... What Is Delavirdine? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Read more »
The Center for AIDS

Rescriptor (Delavirdine)

... Delavirdine tablets are white, capsule-shaped, and marked with "U 3761." Background and Description Dose Food Restrictions Storage Read more »
Test Positive Aware Network

La Guía Annual de Medicamentos para el VIH: Rescriptor (Delavirdine, DLV)

...   Nombre de Marca: Rescriptor Nombre Común: delavirdine (DLV) Clase: análogo no-nucleósido (también llamado inhibidor de la transcriptasa reversa del no-nucleósido, NNRTI o non-nuke, Read more »
The Body PRO

Antiretroviral Drug Interaction Studies Show Favorable Effects

...other handlower nelfinavir blood levels by 82% and should not be co-adminsitered withnelfinavir. Another study combined delavirdine with each of the availableprotease inhibitors to determine the pharmacokinetic interactions amongthese drugs.... Read more »
Connect With Others

Rescriptor (delavirdine mesylate)

Posted by Anonymous
Is anyone taking this drug? Are you experiencing any side affects. I've only been taking it for a week and now I have a cold/allgery problem (watery eyes and nose). I don't know if it the medicine or just a normal cold/allgery. Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply
...went on for several years as I slowly watched my CD4 count drop. I was one of the first people to gain access to Rescriptor (delavirdine), the first of the drug class called NNRTIs. But this turned out to be another big mistake. Later drugs in... Read more »