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Saquinavir Interactions

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AIDS InfoNet

Saquinavir (Invirase)

What Is Saquinavir? Saquinavir, also called Invirase, is a drug used as part of antiretroviral therapy (ART). There used to be a version called Fortovase that is no longer made. Saquinavir is manufactured by Roche Laboratories. Saquinavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus....
Ask the Experts

saquinavir with abacavir?

I have been on saquinavir, lumivudine, and d4t since diagnosis in 1998 when my T4s were clear down to 35. They have slowly climbed to 300 and my viral load has been undetectable for some time. I eat and exercise quite well but lypoatrophy...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
I would not have any concern over the saquinavir which is generally a well tolerated drug. There are no interactions between saquinavir and abacavir so there would be no problem changing the d4t to abacavir. The benefits of switching, however, will... Read more »

switched to Ratonavir/Saquinavir question

Dr. Gallant: I just read you answer to the February 7th question on switching toRatonavir and Saquinavir. Now I am reallyconfused. I took your suggestion and went on 400mg of Ratonavir and 400mg. of Saquinavir bid. I am really fatiqued andfeel...
Joel Gallant, M.D.

Response from Joel Gallant, M.D.

Johns Hopkins University, School of Medicine
You don't waste any time! Please remember that I'm not here to give "suggestions"-- those should come from your doctor. But since you've already changed your therapy, I'll just make a few comments on the... Read more »

saquinavir

would you do me a favor?i need pictures of package of saquinavir.it's very important to me and my life.could you describe small package of saquinavir?are there 3 line on the package of that?please tell me ....i must know what packages of...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Pictures would be difficult to reproduce here--Inverase is a green and yellow capsule that says "Roche 0245" on the side.Fortovase is a larger tan colored capsule that says "Roche 0246".Hope this helps. BY... Read more »

SAQUINAVIR GELCAPS

Should all patients on Saquinavir be switched to gelcaps? a medical provider...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
When the soft-gel caps are released, it would seem reasonable to switch everyoneover from the old formulation to the new one, since you will be able to achieve higher drug levels with somewhat fewer pills.... Read more »
Connect With Others

Med resistance on Norvir/Saquinivar..anyone else?

Posted by Anonymous, 1 Reply
I have been on Norvir/Saquinavir for 7 years. Starting to show resistance. Panicking a little, they worked for so long,
controlled side effects. Doctor wants to do labs more frequently for now but not switch, maybe add another drug.
Has anyone gone... Read more »

Fatigue

Posted by Anonymous
I am on Norvir/Saquinavir. HIV+ since 1990. I have noticed that sometimes I just plain feel like CRAP...a fatigue that resembles the flu. Sometimes lasts one day, sometimes a few. Don't know if HIV "related", or possibly side effects of the meds.... Read more »

For those on the Atripla regimen

Posted by Pos_in_Thailand
I am giving a URL for a very interesting and complete drug interactions database. If you are on Atripla, and are on or will be needing to take any medication for any reason, you can type it's name in the search and see if there is a known... Read more »

Its me...AGAIN

Posted by sadface, 5 Replies
Hi friends,
Of course I have to be a bigger pain in the ***. I was wondering, I have had a flu shot back in September...do you think that has ANY interaction with my results being behind in their results??? Serconvertion? My exposure was middle of... Read more »

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