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Ritonavir Boosting

Here's a taste of what has to offer on this topic:
U.S. Food and Drug Administration

FDA Drug Safety Communication: Important Drug Interactions Between Victrelis (Boceprevir) and Ritonavir-Boosted Human Immunodeficiency Virus (HIV) Protease Inhibitor Drugs

Safety Announcement Facts About Victrelis (Boceprevir) and HIV Protease Inhibitors Victrelis is a hepatitis C virus (HCV) protease inhibitor used with the medicines peginterferon alfa and ribavirin to treat chronic (long-lasting) hepatitis C... Read more »
Merck & Co., Inc.

Important Drug Warning: Results of Pharmacokinetic Study in Healthy Volunteers Given Victrelis (Boceprevir) and Ritonavir-Boosted HIV Protease Inhibitors May Indicate Clinically Significant Drug Interactions for Patients Coinfected With Chronic Hepatitis C and HIV

Dear Health Care Professional, The purpose of this communication is to inform you of recent pharmacokinetic study results evaluating drug interactions between VICTRELIS, an oral chronic hepatitis C virus (HCV) NS3/4A protease inhibitor, and... Read more »
HIV i-Base

Cobicistat Compared to Ritonavir to Boost Atazanavir in Treatment-Naive Patients

Results from a recent randomized, double-blind, double placebo, phase III study comparing cobicistat to ritonavir to boost atazanavir were published in the 26 March edition of the Journal of Infectious Diseases . 1 Cobicistat is an inhibitor of... Read more »
Ask the Experts

Which Boosted PI

I am about to start first line treatment with either atazanavir or saquinavir (boosted with ritonavir) and Tenofovir.After reading about effacy and side effects I dont know which PI to chose.CD4 = 280VL = 40000% = 12...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.I'll assume that your doctor will be prescribing either 3TC (Epivir) or FTC (in combination with tenofovir as Truvada).There have been a couple of recent updates to US-based treatment guidelines from the <a... Read more »


Hello, I am currently a pharmacy student and I have a question about ritonavir. Due to manufacturers increase price on ritonavir, is there another HIV med or upcoming HIV med that you may know which can potentially take the place of ritonavir as a...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
A multi-million $$ question--alas-no drug is on the immediate horizon to my knowledge that would function like ritonavir in boosted regimens. KH... Read more »

Twice daily dosing of Crixivan without Ritonavir

Has the twice a day dosing of Crixivan (in combination with Combivir) been abandoned or is it still being studied. I am speaking of 1200mg. of Crixivan without the boost of Ritonavir....
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
Dosing Crixivan (indinavir) at 1200mg twice daily in combination with nucleoside reverse transcriptase inhibitors (for example, Combivir) has been studied and abandoned because of a high rate of failure among the patients who took it. The ONLY... Read more »

No replacements for ritonavir in the works?

Hello, wonderful doctor people! I've been following the scandal/hubbub over ritonavir since the price increase happened last December, and noticed that a lot of the complaints of docs like you and activists stem from the fact that ritonavir is...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
The ritonvir price increase just happened. Even imagining that there is a ritonavir-like drug on some pharmaceutical company shelf somewhere, the company would need to embark on a series of clinicial studies to demonstrate the safety and efficacy... Read more »
Connect With Others


Posted by Anonymous, 1 Reply
I'm looking to talk with people who are currently taking
ritonavir (Norvir) capsules and will be affected by the imminent
change to liquid ritonavir. I'm a reporter working on a story for
the journal... Read more »

ritonavir in liquid form

Posted by Anonymous, 1 Reply
My partner just started taking ritonavir in the liquid form and it
tastes really bad. Furthermore, after taking it, he becomes very
nauseous and weak. We would like to hear from people with
... Read more »

Need Ritonavir

Posted by Anonymous
Dear Friends

I am a person living with HIV for 11 years now. Up until now I have not taken any medications apart from vitamin supplements. I have been in conflict with myself on whether to start HAART and after much sole searching have decided to... Read more »

I need to boost my friend's spirit

Posted by Anonymous, 1 Reply
Recently found out that a gay male friend is HIV. We have known each other all of our lives. I love him just like a brother. I want to help him in everyway that is possible. I want him to know that I care no mattter what! I want him to find the best... Read more »