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Risks Starting Treatment With Low Cd4

Here's a taste of what has to offer on this topic:
Get the Facts
The Well Project

Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). As the immune system loses CD4 cells, it becomes weaker and is less able tofight off germs. When it...
Ask the Experts


Hi,I was diagnosed with HIV around 15 months ago. Since then my health has been good (especially in the last six months) but my CD4 count has fallen a bit rapidly from 470 to 371 to 324 over this time period. However, my CD4 percentage count has...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,You are correct: The CD4% is generally considered the more accurate indicator of immune integrity, as it doesn't tend to fluctuate as much due to intercurrent illnesses and other non-HIV-related factors. (See below.)Regarding beginning... Read more »

Cancer risk: what's worst, high cd4 but not on meds or low cd4 but suppressed?

High Dr McGowan,My close friend has just been diagnosed with lymphoma. He is HIV positive but not on medication. He has a high CD4 count (greater than 600, and good percentage). This was a shock given his strong immune system, so my question is, in...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Dear Michael,Sorry to hear about your friend. Most experience has been with people getting cancers and lymphomas with low CD4 counts. In that case people do well by starting antiretroviral treatment along with the chemotherapy and survival rates... Read more »


Hi BenI recently found this study that suggests starting treatment at lower CD4 counts causes a MUCH greater risk of treatment failure. I started at around 80 T cells, with a boosted protease regimin, and have been undetectable for a year with no...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello Michael and thanks for your post.The study that you've cited is one from our HOPS study colleagues- this study doesn't conclude that persons with low CD4s are more likely to have treatment failure, rather, it says that if someone... Read more »

Low CD4, OK CD4 Count, Start Treatment?

Without going into a lot of treatment history, I have been positive since October 1999. I've never had any drugs bring my viral load down to undetecable and my last resistance test, Nov 03, shows I'm now also resistant to Kaletra, along...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Since your overall CD4 count is high I would not worry about the low percentage. If the resistance test showed that the virus is resistant to Kaletra then Reyataz is not going to pass muster. In fact, you might strongly consider trying to hold off... Read more »
Connect With Others

treatment starting at higher cd4

Posted by alive2, 1 Reply
now that people are being told to start medication at a higher cd 4 number does this pose a bit of apprehencion? will the first prescribed medications last longer? is it a ploy by big pharmacutical companies?
to me i worry when the cdc or reports... Read more »

Help! BF has low CD4 and high VL

Posted by LoveofMyLife, 2 Replies
Hi everyone. I'm negative. My bf has been positive for 21 years. He has been non-compliant with his meds off and on over the years. This week, we found out that his CD4 is 65 and VL is 80,000. His doc (an HIV Specialist) is doing the resistance... Read more »

Unusual case. Ongoing Low CD4 - HIV possible?

Posted by Tryin2BRational, 4 Replies
I wrote awhile back outlining a one-time risky exposure in March 2006(unprotected vaginal sex) with a female of unknown status. I contacted her and she told me she did not have HIV, but I doubted her veracity (I had two consectutive rounds of... Read more »

Negative but with a very low CD4 and CD4/CD8

Posted by tobeabetterman, 1 Reply
Hi everyone , sorry to bother again .
I was once told by dear kicker and riverprincess that my 3 months result is conclusive , thank you very much with my best wishes , and I'm sorry I have bother you again .
Some new situation make me nervous again .... Read more »