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Risks Of Fusion Inhibitors

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Fusion and Attachment Inhibitors

... Attachment and Fusion Inhibitors Attachment and Fusion Inhibitors in Development Drugs No Longer in Development Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase
Ask the Experts

cervical spine fusion surgery healing with hiv

I am going to have surgercal spine fusion surgery and would like to know if there is any problem with bone grafting or fusion in the neck. My cd4 is 108 and viral load is 170. My labs are continuing to get better monthly.
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
HIV infected patients generally do well with surgery particularly if nutrition/hygiene status is good and their HIV infection is well controlled with medication. KH Read more »

fusion inhibitors

Is there a pill form of any fusion inhibitors coming soon?
Don Kurtyka, ARNP

Response from Don Kurtyka, ARNP

University of South Florida School of Medicine
...Fuzeon is the only fusion inhibitor currently approved by the FDA. Fusion inhibitors are part of a bigger classification of drugs called entry inhibitors Read more »

Fusion inhibitors

I would very much like to know if fusion inhibitors are going to produce loss or fat acumulations like protease inh., and if the new Tenofovir has more of these kind of side effects than other transcriptase inhibitors. Thank you
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...T-20 (the only fusion inhibitor in wide use) has not been associated with lipodystrophy yet. Since it works extracellularly there is hope that some Read more »

Fusion Inhibitors

Can you shed any light on what, if any, of the preliminary reports on fusion inhibitors may include as far as side effects? I guess I am assuming they have done some human trials??
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...T-20 = Fuzeon is the only fusion inhibitor soon to be more widely available. Since it acts outside of cells (blocking fusion) its toxicity would be expected Read more »
The Body

Steaming Hot Monkey Fusion Sex!

...with the three types of hot monkey sex described above; consequently, I wanted to discuss yet another variation: hot monkey FUSION sex. It's central to understanding my response to a persistent "QTND" (question that never dies). That eternal... Read more »
Women Alive

Fusion and Fusion Inhibitors -- Understanding the News

...Pharmaceuticals, a New Yorkbased company researcher of HIV co-receptors, haveannounced a collaboration to find a drug that willinhibit fusion. It may be time for a little update onthe subject. Replication Reverse-TranscriptaseInhibitors ( such... Read more »
Seattle Treatment Education Project

A New Type of Anti-HIV Drugs: Fusion Inhibitors

... The fusion inhibitor that is the furthest along in development is called T-20. It interferes with HIV entering a cell by binding to part Read more »
Henry J. Kaiser Family Foundation

Roche, Trimeris Halt Clinical Trials of New Fusion Inhibitor T-1249

...which received FDA approval in March 2003 (Pierson/Berkrot, Reuters , 1/6). Fuzeon, which is in a new class of drugs called fusion inhibitors, has encountered resistance from doctors and patients because of its high cost and injection... Read more »
Connect With Others

Fusion Inhibitor News?

Posted by Anonymous
...Does anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the Read more »

can anyone tell me

Posted by Anonymous, 7 Replies
why does carolyn salisbury say you need to test up until 12 months and you guys say 3 months? She is on ask the expert board. please I need details to why Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply have been described as "PAART," since it was only partially active for me. In 2002 I enrolled in a trial of the first fusion inhibitor, T-20 (Fuzeon), after nagging investigators and the companies developing the drug (Roche and Trimeris)... Read more »

Tough to be human!!!

Posted by Anonymous, 1 Reply
...if I were positive it would at least 4-5 years (without meds) before I would start to have medical problems. With new meds, fusion inhibitors, integrase inhibitors, IL-2, vaccine trials... etc. it's only getting better. Granted it's not all... Read more »