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Risks Of Zidovudine

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AIDS InfoNet

Zidovudine (Retrovir, AZT)

What Is Zidovudine? Who Should Take Zidovudine? What About Drug Resistance? How Is Zidovudine Taken? What Are the Side Effects? How Does Zidovudine React With Other Drugs? What Is Zidovudine? Zidovudine (Retrovir) is a drug used for antiretroviral therapy (ART). It was first manufactured by GlaxoSmithKline. It is manufactured by ViiV Healthcare. The patent on zidovudine expired in 2005 and several generic versions have been...
Ask the Experts

zidovudine

under which of the following conditions is azt (zidovudine) prescribed for patients suffering from hiv?...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Zidovudine (AZT, Retrovir) is used as part of combination therapy for the treatment of HIV-infected individuals or in special circumstances for the prevention of HIV infection, following high-risk exposure. BY... Read more »

Underdosage of Zidovudine

Dear SirI am writing for the 2nd time. My son aged 5 years has been recently diagnosed as HIV+ His CD4 is 384. His doctor started him on Zidovudine 6ml twice a day, Lamivir 6.5 ml twice a day, and Nevirapine (initially 6 ml once a day). His weight...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.This reply comes from our good friend and colleague, Andy Pavia, MD from University of Utah:I don't think there is any risk at all from 2 weeks of underdosing of zidovudine. First of all, zidovudine resistance develops... Read more »

atripla and zidovudine

if somebody becomes resistant to atripla components would he necessarily become resistant to zidovudine as well? i hope not because in a paper i saw point mutations caused by 3 components of atripla are absolutely different from that caused by...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for posting.There is a potential for cross resistance among the components of treatment. This means that prolonged treatment failure of one NRTI regimen has the potential to cause significant cross resistant to other medications of... Read more »

Switch from Zidovudine

My wife with a baseline CD4 of 83 (12.8%), and viral load of 2071 is on Zidovudine, Lamivudine, and Nevirapine for 6 weeks. She is also taking Bactrim DS for 2 weeks. While she has tolerated the drugs, she has recently reported a decline in white...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
You ask a very analytical question. Your doctor is right in that the combination of Bactrim and zidovudine may be particularly bad for the white blood cells, especially in someone who is deficient in folate. Sometimes, before making any changes in... Read more »
Connect With Others

What is my overall risk of get HIV?

Posted by francisco23016, 1 Reply
Hi,

I am Rodrigo. I write because I have inquiries about risks of transmission of HIV. Three weeks ago, I had receptive and protected anal sex ( we used condom which did not break) with a guy whom has HIV (I realized of that the next morning of the... Read more »

What is my risk?

Posted by francisco23016, 1 Reply
Hi there,

I write here because I have inquiries of transmission of HIV. Two months ago, I had receptive and protected anal sex ( we used condom which did not break) with a guy whom has HIV (I realized of that the next morning of the intercourse).... Read more »

Low Risk/High Risk

Posted by Anonymous, 1 Reply
What does Low Risk/High Risk mean? I mean, how many low risk people turn positive? Obviously, high risk people have a better chance of testing positive, but does low risk mean that the risk is virtually none? Thanx.

Read more »

High risk and low risk and their conclusive result periods

Posted by optiplex, 2 Replies
Window period should be same for all cases whether its high risk or low risk. There are cases where people got infected through low risk and came out clean even after high risk exposure.
virus cycle is going to be remain same in someone got infected... Read more »