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Risks Of PIs

Here's a taste of what TheBody.com has to offer on this topic:
Ask the Experts

Logical order in PI's?

In absence of previous treatments on PI's and based on the usual mutations that appear is there a "more logical order" when beginning a PI based treatment? (I'm speaking OF 908, KALETRA,REYATAZ)
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...that can ignite quite a debate among HIV experts. My own thinking on this reflects the unique ability of ritonavir boosted PIs to be not only potent but also to be able to reduce the risk of PI resistance, even in those failing regimens that... Read more »

NNRTI vs. PI Combo

Hello,Why would a doctor prescribe a PI based regimen over a NNRTI regimen for treatment naive... Read more »

Changing Meds to Avoid PI Complications -- 2nd Opinion please

I have been on Combivir/Crixivan since Feb. /98. When I started VL was 98000 and CD4 was 484. By... Read more »
Articles
The Body

Women and HIV in the U.S.: A Focus on A&PI Women

...coming decade. Within three to four years, the incidence rate jumped 10-16 percent. It is estimated that two-thirds of A&PIs have never been tested -- for A&PI women, I have a strong feeling that this rate is higher. The power dynamics of... Read more »
The Body PRO

Dual-PI Regimen Preferred Over Single-PI Regimen After Initial PI Failure

...previously achieved an undetectable HIV RNA (less than 500 copies/mL). The treatment arms included one new PI versus two new PIs, both in combination with an NNRTI and one or more nucleosides. At 12 months, the percentage of patients achieving an... Read more »
The Body PRO

Color Doppler Ultrasonographic Comparison of PI vs. NNRTI Regimens

...status. No difference was found among the three groups in intima thickness. This was a surprise because we were all expecting that PIs would be bad. The UCSF study showed -- in its longitudinal part -- that patients on PIs had more rapid... Read more »
International Association of Physicians in AIDS Care

Fosamprenavir: A New PI Option

... The improved tolerability, dosing flexibility, and resistance properties of new protease inhibitors (PIs) have triggered a reassessment of the role that PIs may play in first- and second-line antiretroviral therapy. The US Food and Read more »
Connect With Others

PI Monotherapy advice

Posted by logopolis, 2 Replies
Admin OptionsEdit Discussion Close Discussion Edit Your Tags Cancel Delete Discussion Hi, My partner has been asked to take part in a clinical trial - Protease Inhibitor monotherapy versus Triple Therapy. Just gathering some info before he... Read more »

Prezista - New PI designed for Resistant Virus

Posted by Survivor, 2 Replies
...on Friday approved the use of a new HIV drug, made by Johnson & Johnson <JNJ.N>, in combination with related therapies to help treat patients who do not first improve with other treatment. The drug, Prezista, is a protease inhibitor... Read more »

hyperthyroidism and PI's

Posted by lis
...hey everyone, i've been pos since 86, started med in 2002, went through a couple different regiems, and now find myself on 2 PI's along with epivir and veread for the last year. my question .. has anyone else experianced hyperthyroid issues from... Read more »

P.I. versus NNRTI

Posted by Anonymous, 2 Replies
Hi. I am hearing a lot of good things about the Truvada + Reyataz + Norvir combo. I am just about to commence my first line regimen, and wanted to enquire as to what anybody else thought of this combo? I am starting therapy with a relatively high... Read more »