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Risks Of Nelfinavir

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AIDSinfo

An Overview of Viracept (Nelfinavir)

nel-FIN-a-veer --> Brand Name: Viracept Other Name(s): NFV, nelfinavir mesylate Drug Class: Protease Inhibitors Approved Use: Treatment of HIV Infection WARNING: Nelfinavir can cause serious, life-threatening side effects. These include liver problems in people with moderate or severe liver impairment and life-threatening drug interactions. Nelfinavir oral powder contains aspartame and should not be used by people with...
Ask the Experts

Nelfinavir -v- Nelfinavir/Saquinavir Combo

I have been on AZT, 3TC and Crixivan since last December and my VL has dropped to (last reading) 175. However, I amseriously considering a switch from Crixivan to Nelfinavir (Viracept) because ofthe friendlier dosing schedule, and removalof the risk...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
There may be a benefit to using saquinavir in addition to nelfinavir, but we really don't know yet. Nelfinavir doesn't increase saquinavir levels as much asritonavir does. In the only studies being done on this combination, they're... Read more »

Nelfinavir

Dear Dr.I read on this Forum and in the new Medscape guidelines that Nelfinavir can now be used 5 cap every 12 hours. Is this safe considering the half-life of this medication is 3.5 - 5 hours? Isn't there a higher risk for developing...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
The potency appears to be the same when the twice versus three times a day regimens were compared. Side effects were no different. Sorry you got me. What is Biovir? I would simplify your life and switch to the twice a day regimen and take it with... Read more »

Worried about Nelfinavir Resistance

Hi, and firstly congratulations on one of the most informative and helpful HIV sites on the net. OK, my question is about developing resistance to Nelfinavir. I started my first combo 11.5 months ago and it is Videx EC, Zerit, Viracept...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
I am not clear whether you are taking nelfinavir twice a day or three times a day - if you are taking it twice a day, I personally am not a fan of this regimen. I do not think that the nelfinavir levels are as high as I would like using the drug... Read more »

PEP Kit/Combivir & Nelfinavir

Hello.I was assaulted by an aquaintance. He had a vl of 90,000 and cd4 of 200.He stuck his fingernails in me and when we fell to the ground he cut his hand and may have had his blood enter my open cuts.He went with me to the Emergency and within...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The vast majority of patients have no liver or pancreatic damage from 4 weeks of PEP with the regimen you have been given. There is no clear data supporting use of 1 versus 4 weeks of a PEP regimen so the recommendations are fairly empiric. The... Read more »
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Low Risk/High Risk

Posted by Anonymous, 1 Reply
What does Low Risk/High Risk mean? I mean, how many low risk people turn positive? Obviously, high risk people have a better chance of testing positive, but does low risk mean that the risk is virtually none? Thanx.

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Low Risk..Yet still a risk IMHO, opinios?

Posted by Anonymous, 1 Reply
"Made out" (Sexual contact but no oral, anal, or unprotected sex, mostly deep kissing/sucking on nipple) with a girl who's sexual history has suddenly come into question when she mentioned in passing a few days ago her ex-boyfriend may have shown up... Read more »

Low risk or no risk, please answer?

Posted by Anonymous, 1 Reply
I was grinding/frottage with a female of unknown status. She had her underwear on and I had mine on as well. Is there any risk in this at all? My Dept of Health wouldn't give me a straight answer. Thanks and God Bless. Read more »

Sanitary Pads - Real risk or no risk?

Posted by Anonymous, 1 Reply
Hi,
I was walking a dark alley near my place when I stumbled upon a sanitary pad. Not sure if it was soiled or not, although I believe it was unused since it looked clean even in the dark. I was wearing flip-flops at the time and I had a small... Read more »

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