Risks Of Maraviroc

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An Overview of Selzentry (Maraviroc, Celsentri)

mah-RAV-er-rock Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV from entering human cells. Indications and Usage Maraviroc received accelerated approval on August 6, 2007, and traditional approval on November 25, 2008, by the FDA for the treatment...

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Maraviroc study or not?

Hi Dr. Daar, Thank you in advance for your time and energy for this site! I am a long term surviver, (21 years) and very drug experienced. I have reached another cross roads in my HIV journey. I have just completed the tests to see if I am R5...

Response from Eric Daar, M.D.

UCLA School of Medicine

I will start by making some general comments and then specifics regarding your situation. Anytime someone is "failing" their antiretroviral treatment it is worth defining whether that is because their viral load has rebounded, because... Read more »

new development in the drug Maraviroc

Dear Dr.Bob,Hope you are well.I was just watching the news in England when a story about the HIV drug called Maraviroc was discussed. It was said that in a few months the drug will be available on the NHS (national health service in England). As you...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi,Maraviroc is in a new class of anti-HIV drugs called "CCR5 Inhibitors." They target a very early stage in the infection process the cell-entry stage. These drugs have been in development for quite some time and maraviroc is primed to... Read more »

Maraviroc

My viral load has become detectable and my doctor would like to put me on Maraviroc and Isentress. I have been reviewing both of these drugs and I have some concerns with Maraviroc. I know it works on the CCR5 but what is known about the CCR5...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

The CCR5 receptor is a receptor on the CD4 T cell. It is used as a 2nd (or co-) receptor for HIV to enter the T cell. HIV may also use another co-receptor (called CXCR4) to enter the cell. Since maraviroc only blocks virus that use CCR5, it is... Read more »

maraviroc

hi drgood morninghope all is well on your side.i am a male of 30 newly diagnosed with hiv during a blood donation camp.in couple of days my lab results for cd4 and viral load will be out and i will see an hiv specialist for the drug regimen.i read...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

There is comparativey little info about use of CCR5 inhibitors like maraviroc for initial treatment of HIV infection. Since the success rates for initial therapy with current often simple (once daily ) regimens is now fairly high (often > 90%)... Read more »

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Low Risk/High Risk

Posted by Anonymous, 1 Reply

What does Low Risk/High Risk mean? I mean, how many low risk people turn positive? Obviously, high risk people have a better chance of testing positive, but does low risk mean that the risk is virtually none? Thanx.

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Low Risk..Yet still a risk IMHO, opinios?

Posted by Anonymous, 1 Reply

"Made out" (Sexual contact but no oral, anal, or unprotected sex, mostly deep kissing/sucking on nipple) with a girl who's sexual history has suddenly come into question when she mentioned in passing a few days ago her ex-boyfriend may have shown up... Read more »

Low risk or no risk, please answer?

Posted by Anonymous, 1 Reply

I was grinding/frottage with a female of unknown status. She had her underwear on and I had mine on as well. Is there any risk in this at all? My Dept of Health wouldn't give me a straight answer. Thanks and God Bless. Read more »

Sanitary Pads - Real risk or no risk?

Posted by Anonymous, 1 Reply

Hi,
I was walking a dark alley near my place when I stumbled upon a sanitary pad. Not sure if it was soiled or not, although I believe it was unused since it looked clean even in the dark. I was wearing flip-flops at the time and I had a small... Read more »

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