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Risks Of Didanosine

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Get the Facts
AIDS InfoNet

Didanosine (Videx, ddI)

...Didanosine React With Other Drugs? What Is Didanosine? ddI (Videx) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Didanosine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse...
Ask the Experts

Vision Changes with Didanosine

My partner had his meds changed two months ago and two weeks ago had a sudden change in vision. He now has to squint to focus day or night and is seemingly more light sensitive than normal. We discussed this with our doctor who said we most likely...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
...prescription lenses can occur quickly at some ages (esp mid-40s). This is a change in lens shape. Reports mostly with high doses of ddI of visual changes were related to retinal (back of the eye) problems and were generally reversible on drug... Read more »

neuropathy pain (didanosine+stavudine+efavirenz)

Dear Dr Robert J. Frascino, I'm sure many patients email you a lot of times regarding this matter. But I really really hope you won't get bored. I'd really really appreciate your help, time and patience!My question is:My father CD4 recently = 480He...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hi Tom,Didanosine (ddI) plus stavudine (d4T) is no longer a recommended combination! It has been found to be less effective and substantially more toxic Read more »

HCV with deterating CD4 on HIV

I have been on the HCV treatment for 2 weeks now and just got my results back on my HIV CD4 and Viral Loads prior to the starting of treatment. My results were CD4 214 and VL 93050 but the HCV specialist doesn't want me to start HIV meds until the...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
...within about 4 to 6 weeks. Avoid zidovudine, which increases the risk of anemia while on ribavirin; also do NOT take didanosine (ddI), which can be hazardous due to a drug interaction with ribavirin. Read more »

zidovudine, didanosine, kaletra

Is the above combination suitable for one considered to be resistant to combivir and effavirenz? I have come across these in the internet. My doctor thinks I could be resistant to combivir and effavirenz. I have been on them for 2 years. Due to...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Ideally speaking, if resistance develops to a HAART (highly active antiretroviral therapy) regimen, I recommend getting a resistance test to help guide the choice of the next regimen. If resistance testing is not an option in Zimbabwe and your... Read more »
Articles
Henry J. Kaiser Family Foundation

Examination of Antiretrovirals Abacavir, Didanosine's Potential Link to Increased Risk of Heart Attack Continues

...Reaction, Comments "We were unable to show any increased risk in heart attacks," Gwenan White, a GSK spokesperson, said, adding that the Lancet study results are "inconclusive" (AP/ International Herald Tribune , 4/2). In a linked comment... Read more »
The Body PRO

Abacavir, Didanosine Associated With Higher Heart Attack Risk, D:A:D Study Finds

...it's in your body that may be associated with an altered risk of cardiovascular disease. Click to enlarge For additional images from this study, click here . If these associations are biologically real, what are the biological... Read more »
AIDSinfo

An Overview of Videx (Didanosine, ddI)

... Brand Name: Videx EC, Videx Other Name(s): BMY 40900, BRN 3619529, CCRIS 805, Didanosina, Dideoxyinosine, HSDB 6548, ddI Drug Class: Nucleoside Reverse Transcriptase Inhibitors Didanosine, also known as ddI or Videx, is a type of... Read more »
The Body PRO

Abstract No. 402:Phase I/II Dosing Study of Once-Daily Hydroxyurea (HU) Alone vs Didanosine (ddI) Alone vs ddI + HU

...In earlier studies, hydroxyurea, when added to DDI or D4T increased the activity of a single or dual nucleoside therapy by 0.5 to 0.7 log 10 copies/mL. The authors, in this placebo Read more »
Connect With Others

Early HIV Treatment Failure Linked to Didanosine/T

Posted by TwinsDad, 1 Reply
...NEW YORK (Reuters Health) Aug 23 - The combination of the antiretroviral agents didanosine, tenofovir, and efavirenz is associated with a high virological failure rate in treatment-naive patients with HIV, British investigators Read more »

50% of HIV+ Develop Neurocognitive Impairment

Posted by ScotCharles, 3 Replies
...remembering, planning, making decisions, attentional abilities, concentration; those kinds of skills are under "neurocognitive." In addition, a subset of these patients received brain-imaging studies, including studies of the structure of their... Read more »

Am I Infected

Posted by delhiguy, 3 Replies
I am 30 YO guy. Worried that I may have got infected. I met this friend of mine on 5th of Dec 2010 which was just a causual meeting after 5 years. After having drinks she started touching me and I got aroused and we end up mating. While in act, she... Read more »

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »