Risks Of Atazanavir

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Atazanavir (Reyataz)

What Is Atazanavir? Atazanavir, also called Reyataz, is a drug used as part of antiretroviral therapy (ART). Atazanavir is a protease inhibitor manufactured by Bristol-Myers Squibb. Atazanavir was approved by the FDA in 2003. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Protease inhibitors prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV...

Ask the Experts

Will switching to Atazanavir reverse the weight gain and fat deposits?

it has recently been recommended that I stop taking nelfinavir and replace it with atazanavir boosted with ritonavir in order to halt the progression of lipodystrophy. I will continue to take nevirapine and 3TC. What is the evidence that this will...

Response from Brian Conway, M.D.

University of British Columbia

This is an interesting question. The regimen you are now taking carries a limited risk of any lipodystrophy. This being said, there are a few case reports of reversal of body shape abnormalities following a switch from another protease inhibitor... Read more »

Atazanavir

Will Atazanavir not cause lipo as have other PI's? What about Tripranavir? Do you think we can create combo's that do not cause lipo?...

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College

That is one of the most important questions we're currently confronting regarding HIV therapy. Unfortunately, at this point we don't have an answer, although some studies indicate that the risk of lipodystrophy is lower in non-nucleoside... Read more »

atazanavir

I would like to know if the atazanavir is able to provoke lipodistrophy?thanks. Tulio from Rio de Janeiro....

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital

A study over 1 year did not find any fat loss or metabolic disturbances. Many physicians now think the choice of nucleoside analog (NRTI) is more important than the choice of PI for the risk of body shape changes. However, in terms of metabolic... Read more »

Kaletra vs Atazanavir for diarrhea

I am currently taking Kaletra, Viread, Ziagen and 3TC and having terrible problems with diarrhea. I know it's the Kaletra as I was on the other meds in the past and had none. I've tried all the usual routes--immodium, lomotil, calcium...

Response from Brian Conway, M.D.

University of British Columbia

It would be important to make sure (by tests on your stool and perhaps even other tests) that there is not a specific cause for your diarrhea other than the medications. This being said, it is quite possible that it may be a side effect of the... Read more »

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Need Atazanavir

Posted by princealbert, 1 Reply

Does anyone know how to access atazanavir, a new protease inhibitor not yet approved? I've got less than 20 CD4, VL 40,000, am multi-drug resistant, and don't have too many options left. I might be getting T-20, but need another good drug to add to... Read more »

Those taking, Raltegravir, Truvada & Atazanavir

Posted by sweetvanilla27, 1 Reply

I am wanting to hear from anyone who have experienced taking Raltegravir, Truvada & Atazanavir and how you have got on with the meds?

I first started taking meds in May this year I was put on Truvda and Sustiva first, and was taken off them due... Read more »

need atazanavir

Posted by princealbert

Low Risk/High Risk

Posted by Anonymous, 1 Reply

What does Low Risk/High Risk mean? I mean, how many low risk people turn positive? Obviously, high risk people have a better chance of testing positive, but does low risk mean that the risk is virtually none? Thanx.

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