Resistance After Pep Hiv

Here's a taste of what TheBody.com has to offer on this topic:

Get the Facts

Treatment After Exposure to HIV

For serious exposures, the U.S. Public Health Service recommends using a combination of three approved ARVs for four weeks. For less serious exposure, the guidelines recommend four weeks of treatment with two drugs: zidovudine (Retrovir, AZT) and lamivudine (Epivir, 3TC). In January 2001, the Centers for Disease Control warned against using nevirapine (Viramune) for PEP because of the risk of liver damage. See Fact Sheet 431 for more...

Ask the Experts

Does PEP lead to resistancy?

Dear Dr Remien,My boyfriend is HIV+ and I'm not. I'm glad to be able to tell you that we haven't had one accident yet. But I'm interested in Post Exposure Profylaxe, because you never know. I heard that when you've used PEP...

Response from Robert H. Remien, Ph.D.

Columbia University

You are absolutely right when you say it is the virus that becomes "resistant," not the person. I have never heard that after taking PEP once, the person is at risk for developing resistance. Resistance develops when a drug is present... Read more »

after taking PEP fear of possible virus resistance

Dear Doc,I need ur opinion as HIV expert maybe u can help me.I am on holiday in Thailand for about 4 months.At the begining of mai i had risky exposure to a sex worker who was positive.I had Elisa test which was negative.I started...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi,1. I think you may have misinterpreted what you read. If you've had a significant HIV exposure and take PEP within the 72-hour window and complete the full 28-day course, there are two potential outcomes: (1) PEP works and aborts the HIV... Read more »

PEP failure and drug resistance?

Hi, I started PEP about three weeks ago with Combivir alone. Recently I started developing symptoms (like swollen neck glands and neck pain, groin pain, fever, burning eyes) which make me feel that these are due to ARS. How much probable is PEP...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

In general those symptoms in that setting would unlikely be related to HIV infection. The chances for PEP failure relate to the riak of your actual potential HIV exposure. Drug resistance after PEP can occur but is not very common when 2 or more... Read more »

Risks Associated with PEP and Resistance

Dr. Sherer,I have recently finished a 30 day course of PEP (combivir 2X day with strict adherence), and I was discussing with my boyfriend (HIV+) the risks of resistance without adherence.In a situation such as mine, where I had an exposure and...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

The chance that you would experience such a double negative, i.e. a PEP failure AND the development of drug resistance due to the use of a PEP regimen like combivir is extremely small. This is particularly true for the NRTIs, for which resistance... Read more »

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Connect With Others

PEP

Posted by je5872, 2 Replies

has anyone ever taken PEP. I began taking PEP 4 hrs post exposure. I was top with hiv+ guy on no meds when condom broke. i immediately washed and urinated. Has anyone had this experince? do they feel the PEP was effective? Read more »

Help ... HIV or PEP Rash?

Posted by GDog, 1 Reply

About 4 weeks ago I stopped a PEP regimen consisting of Nelfinavir, 3TC and 4DT after 11 days.

I stopped due to a bad rash that developed all over my body (it was hot, red and kinda scaly on my legs, arms, neck, back and some on my chest).

I started... Read more »

GMan-Please read my post (Help!...HIV or PEP Rash)

Posted by GDog, 1 Reply

I see your opinion and expertise are valued in this forum and I would love to have your opinion on my risk level and chances of contracting HIV.

Please read my post below (titled "Help ... HIV or PEP Rash"). Read more »

HIV, PEP, and irradication. What we'll never know.

Posted by Anonymous

The following is just a theory, or a topic for discussion.

Is it possible for a person to get the HIV virus in their body, but then somehow their body kills off the virus and they stay HIV negative? We'll never really know, because the virus would... Read more »

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