Replication Of Hiv Inside Host

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Ask the Experts

Replication mechanism of HIV

Dear Doctor Holodniy,I'll like to ask what is the mechanism of HIV's replication like? Specifically, for the HIV reverse transcriptase, does it convert single strand RNA template to a single strand DNA? If so, how does this single strand...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

The HIV reverse transcriptase enzyme has reverse transcriptase activity that converts the viral HIV RNA to a single strand copy of HIV DNA as well as having DNA-dependent DNA polymerase activity that copies the single DNA strand into another DNA... Read more »

Non CD4 replication

HIV uses CD4 cells to replicate and is blocked by HAART from doing this explaining a VL UD when... Read more »

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C. »

how HIV survives inside the body

How does the virus survive inside the body? I know it uses a certain immune cell to replicate so if... Read more »

Response from Lisa Hightow-Weidman, M.D., M.P.H. »

Go to Ask the Experts »

Articles

How HIV Does (and Does Not) Infect, and How it Replicates

HIV can be spread from person to person, but only by a few means. The most common of these are: exchanging body fluids during sexual activity (semen, vaginal secretions, blood) and sharing used needles. Less commonly, HIV may be transmitted from... Read more »

Elite Controllers Block Integration of HIV DNA Into Host Genome

Alone among those infected with HIV-1, so-called elite controllers spontaneously maintain undetectable levels of viral replication even absent the benefit of anti-retroviral therapy. Now Mathias Lichterfeld of the Massachusetts General Hospital,... Read more »

HIV Found to Replicate Outside CD4 Cells; Discovery Gives Insight Into HIV-related Dementia

In an intriguing new study published last week in PLoS Pathogens , researchers discovered the first solid proof that HIV can replicate itself in cell types other than CD4 cells. The finding potentially opens an important window on our understanding... Read more »

Gene That Prevents HIV From Replicating in Monkeys Could Play Role in New Treatment Options for Humans, Study Says

A gene called TRIM5-alpha that prevents HIV from replicating in rhesus monkeys could provide new treatment options for humans and could help prevent HIV-positive humans from developing AIDS, according to a study published in Jan. 11 issue of the... Read more »

Connect With Others

See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply

The below is plagerized from Gallant ( the guru!)
I know that the present antiretroviral medications do not actually kill the virus.
However, if the medications inhibit the virus from reproducing, doesn't the virus die
by... Read more »

Sbjct: 2nd POST-Virus Replication & OTHER Things

Posted by DUDE

Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces anti-bodies. The body reacts. THink of it like this. If you... Read more »

DUDE'S NEWS -VIRUS REPLICATION

Posted by DUDE

Subject: SECOND POST-Virus Replication & OTHER Things
Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces... Read more »

Replicate....

Posted by Anonymous

The HIV virus replicates 9log10 or 10log10(1000 000 000 or 1000 000 0000) each day. So the estimation of virus are 1000 000 000 New virus each day! so why shouldnt your body respond against so much virus? Get a grip virus replication starts nearly... Read more »

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