Replication Of Hiv In Host Cells

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How HIV Damages the Immune System

Introduction The basic structure of HIV is similar to that of other viruses (Figure 1 ). HIV has a core of genetic material surrounded by a protective sheath, called a capsid . The genetic material in the core is RNA (ribonucleic acid), which contains the information that the virus needs in order to replicate (make more copies of itself) and perform other functions. You can think of RNA as the set of rules the virus follows in order to...

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Replication mechanism of HIV

Dear Doctor Holodniy,I'll like to ask what is the mechanism of HIV's replication like? Specifically, for the HIV reverse transcriptase, does it convert single strand RNA template to a single strand DNA? If so, how does this single strand...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

The HIV reverse transcriptase enzyme has reverse transcriptase activity that converts the viral HIV RNA to a single strand copy of HIV DNA as well as having DNA-dependent DNA polymerase activity that copies the single DNA strand into another DNA... Read more »

Non CD4 replication

HIV uses CD4 cells to replicate and is blocked by HAART from doing this explaining a VL UD when it's successful. But, is there any replication going on in the non CD4 cells that sequester HIV? like lymphnodes, and other tissues? and if so are...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Great question. First, there are CD4+ t cells and monocytes and other cells with CD4 receptors that exist in lymph nodes and other organs, and are not just circulating in the blood. HIV can infect some of these other types of cells and replicate at... Read more »

HIV Replication

Hi Dr. Sherer:Does HIV still replicate or mutates even though a person is undetectable?Thank you....

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

Yes. Even in the presence of a viral load below 50 copies/ml, there is evidence of ongoing replication in sequestered sites of HIV infection such as the central nervous system and the gonads. Different viral evolution patterns have been observed in... Read more »

lymphocytes and viral replication

1)In the context of HIV/HepC co-infection, can T cells be lost without the HIV virus replicating? Or is it the replication itself that depletes the T cells?2)If the HIV virus is replicating, is there always a detectable viral burden in serum, or a...

Response from Barbara McGovern, M.D.

Tufts University School of Medicine

Most, but not all, T cell destruction is by HIV itself. In HIV/HCV patients some studies suggest that T cell responses to HIV medicines are not as good as in HIV patients without Hepatitis C. Some have wondered whether chronic hepatitis C may be a... Read more »

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See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply

The below is plagerized from Gallant ( the guru!)
I know that the present antiretroviral medications do not actually kill the virus.
However, if the medications inhibit the virus from reproducing, doesn't the virus die
by... Read more »

Sbjct: 2nd POST-Virus Replication & OTHER Things

Posted by DUDE

Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces anti-bodies. The body reacts. THink of it like this. If you... Read more »

DUDE'S NEWS -VIRUS REPLICATION

Posted by DUDE

Subject: SECOND POST-Virus Replication & OTHER Things
Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces... Read more »

Replicate....

Posted by Anonymous

The HIV virus replicates 9log10 or 10log10(1000 000 000 or 1000 000 0000) each day. So the estimation of virus are 1000 000 000 New virus each day! so why shouldnt your body respond against so much virus? Get a grip virus replication starts nearly... Read more »

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