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Replication Of Hiv In Host Cells

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Non CD4 replication

HIV uses CD4 cells to replicate and is blocked by HAART from doing this explaining a VL UD when it's successful. But, is there any replication going on in the non CD4 cells that sequester HIV? like lymphnodes, and other tissues? and if so are these...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...Great question. First, there are CD4+ t cells and monocytes and other cells with CD4 receptors that exist in lymph nodes and other organs, and are not just circulating in Read more »

hiv outside the host

Dr. Bob,We have all read that hiv does not survive well outside the body, but what exactly happens... Read more »

A friend of mine is down to non-detectable levels; T-cells are still low. Why?

I am very concerned about my best friend. He tested positive for HIV in November of 2008; he was... Read more »
Articles
The Body PRO

Host T-Cell Control of HIV

... Immune Control and Immune Failure in HIV Infection (Symposium 164) Presented by B. Walker View the original abstract In this session Bruce Walker updated his Read more »
Treatment Action Group

Dendritic Cells in Drag: Inauspicious Debut for HIV Specific CTLs; New Concerns about IL-12; Neutralizing Approaches for "Bad" Cytokines; Parke-Davis Targets Cellular Factors

...wereless encouraging than those from the earlier CMV trial. No significant changes in CD4 or viral parameters were reported, and the cells appeared to have diminished survival after reinfusion, relative to the survival of cells in the CMV trial.... Read more »
The Body

Natural Killer Cells Are Prominent Factors in Control of HIV

...percentage of women -- 43% -- in this study! Hopefully this becomes a trend, instead of an exception to the rule. WEAA04: Host Restriction and Innate Immunity to HIV Infection Oral Abstract Session Time: Wednesday 21 July, 16:30-18:00... Read more »
University Hospital Heidelberg

How HIV Cripples Immune Cells

...stopped completely. The underlying mechanism of this observation was a complete mystery up to now, however. HIV modifies the cell structure system of the host cells Viruses alter the support structures of affected cells, enabling them to... Read more »
Connect With Others

Skipping Doses

Posted by chrisnxs, 2 Replies
Hello Everyone, can someone please elaborate on the severity of skipping meds? My bf is positive and has been on meds for about a year. He's on my insurance and it kills the price down to a point where he can get his meds pretty easily. I discovered... Read more »

White Blood Count Question

Posted by Anonymous, 4 Replies
...elevated would that correspond to a recent HIV exposure? I was not sure if an HIV exposure would cause a decreae in white blood cells or an increase. I realize that neither result would in any way indicate HIV directly, I just was curious how... Read more »

Scientists Discover 'Natural Barrier' to HIV

Posted by MOCHA
...Langerhans cells from 13 human donors, may explain why. When HIV comes in contact with genital mucosa, its ultimate target -- the cells it seeks to hijack and destroy -- are immune system T-cells. But T-cells are relatively far away (in lymph... Read more »

Acute HIV Infection Overview

Posted by Anonymous
...chemokine receptor called CCR5 [17]. Homozygotes for this 32 base pair deletion (CCR5delt32) do not express the receptor at the cell-surface and can only be infected with HIV strains that are able to use other co-receptors, such as CXCR4. Thus,... Read more »