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Replication Cycle For Hiv-1

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HIV life cycle, and how HIV affects the immune system

Hi Rick, When Hiv attaches itself to a lymphocyte, is the lymphocyte actually a gland as in the neck or armpit, and does this then become a reproduction factory for HIV with an abundance of T-cells coming from the gland? Thank you for your...
Rick Sowadsky, M.P.H.

Response from Rick Sowadsky, M.P.H.

Nevada State Health Division AIDS Program
Thank you for your question. HIV infects cells of the immune system called CD4 cells. There are many CD4 cells inside the lymph nodes. These cells can also be found all throughout the body.When HIV enters a CD4 cell, the cell itself becomes a... Read more »

HIV Replication

Hi Dr. Sherer:Does HIV still replicate or mutates even though a person is undetectable?Thank you....
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
Yes. Even in the presence of a viral load below 50 copies/ml, there is evidence of ongoing replication in sequestered sites of HIV infection such as the central nervous system and the gonads. Different viral evolution patterns have been observed in... Read more »

Replication Capacity and HIV disease progression

I recently seroconverted two months ago. Shortly afterwards, the HIV clinic that I being supervised at did a resistance test. Gladly I was found to have no drug resistances, however my Viral Replication Capacity was found to be above average at...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
The replication capacity assay has not been shown to be definitively predictive of disease progression. Your RC is in the normal range, and reflects a wild type virus, that is, one that does not have any resistance mutations. Your don't... Read more »

Replication mechanism of HIV

Dear Doctor Holodniy,I'll like to ask what is the mechanism of HIV's replication like? Specifically, for the HIV reverse transcriptase, does it convert single strand RNA template to a single strand DNA? If so, how does this single strand...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
The HIV reverse transcriptase enzyme has reverse transcriptase activity that converts the viral HIV RNA to a single strand copy of HIV DNA as well as having DNA-dependent DNA polymerase activity that copies the single DNA strand into another DNA... Read more »
Connect With Others

See,I told you HIV replicates a cell's DNA TO RNA

Posted by Anonymous, 1 Reply
The below is plagerized from Gallant ( the guru!)
I know that the present antiretroviral medications do not actually kill the virus.
However, if the medications inhibit the virus from reproducing, doesn't the virus die
by... Read more »

Sbjct: 2nd POST-Virus Replication & OTHER Things

Posted by DUDE
Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces anti-bodies. The body reacts. THink of it like this. If you... Read more »

DUDE'S NEWS -VIRUS REPLICATION

Posted by DUDE
Subject: SECOND POST-Virus Replication & OTHER Things
Fellas fellas fellas,,,,
It's certainly time to move one. These HIV tests are very sensative. If you are infected with the HIV virus (or any virus for that matter)
the human body produces... Read more »

Replicate....

Posted by Anonymous
The HIV virus replicates 9log10 or 10log10(1000 000 000 or 1000 000 0000) each day. So the estimation of virus are 1000 000 000 New virus each day! so why shouldnt your body respond against so much virus? Get a grip virus replication starts nearly... Read more »