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Receptor For Hiv In Susceptible Cells

Here's a taste of what TheBody.com has to offer on this topic:
Articles
Treatment Action Group

CD4 T Cells Specific for Different Pathogens Vary in Susceptibility to HIV Infection

When it comes to susceptibility to HIV infection, not all CD4 T cells are created equal. There are a variety of factors that have been shown to influence how readily HIV gains entry and replicates, with the best-described distinction being between... Read more »
Treatment Action Group

Co-Receptor Conundrum

Since the late 1980s researchers have recognized that HIV isolates (viruses sampled from infected individuals) can be divided into one of two categories based on their ability to replicate in particular cells in the laboratory. Originally, a... Read more »
Henry J. Kaiser Family Foundation

Gene in HIV Makes HIV-2 Susceptible to Immune System Response, Researchers Say

A team of researchers from Oxford University and the U.K. Medical Research Council unit in Gambia have discovered that a gene in HIV, known as the gag gene, makes HIV-2 more susceptible to an immune system response, ANI/DailyIndia.com reports.... Read more »
Ask the Experts

T cell receptor

I know that at Boston Massachusetts General Hospital, they are ready to start a clinical trial to test a new chemio-molecules targeting specifically hiv infected cells, even the latent reservoirs.Do you think thatT-cell receptor may be used as a...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
I am not aware of this trial so do not feel qualified to comment. I would suggest contacting Mass General to find out more and volunteerSorry not to be much useDr Moyle... Read more »

HIV or Meds causing abnormal CD4 receptors?

Dr. Boyle, Do all HIV positive folk have abnormal CD4 cell receptors? If so, is this caused by HIV infection or is it a side effect of meds? How do these abnormalities manifest themselves...do they cause symptoms or compromise immune...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
Your question is a little confusing, but I'll try to give you the answer your looking for. CD4+ T cell deficits are not present in all patients with HIV, and the time to develop signficanty immunocompromise (low CD4+ T cells) may vary widely... Read more »

virual susceptibility test

I was diagnosed HIV+ in Feb-2005. At that time my CD4 was 544 and VL was 24,454. I went for my 6M F/U appt. on Sept-2005, and my numbers were; CD4=288 and VL=62,089. My Dr. suggested to start treatment but is running another set of numbers CD4...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Yup, agree with the plan, provided the numbers are consistent with the last set, or if the CD4 count is lower and viral load higher.... Read more »

co-receptors

What are co-receptors? What is their significance in HIV infection?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Coreceptors are molecules on the surface of a cell, in addition to CD4, that HIV requires to lock onto a cell in order to gain entry and infect the cell.... Read more »
Connect With Others

What is a T-Cell or CD4 Count?

Posted by TheBody
What Is a T-Cell or CD4 Count?

Your T-cell count, also known as a CD4 count, reveals the number of T cells in your body. A T cell is a special kind of white blood cell, and the more you have, the stronger your immune system is. When you were infected... Read more »

IL-2 Induces Sustained CD4 Cell Increases

Posted by Anonymous, 1 Reply
IL-2 Induces Sustained CD4 Cell Increases in HIV-Infected Patients


By Deborah Mitchell

TORONTO, Sep 20 (Reuters Health) - The addition of recombinant interleukin-2 (IL-2) to an HIV antiretroviral therapy produces an increase in CD4+ T-cell counts,... Read more »

How Soon Should T-Cell Count Increase?

Posted by Anonymous, 5 Replies
I was infected in October 2003, diagnosed in December 2003, and went on Sustiva and Combivir December 30, 2003. My viral load went from an initial count of 125,000 down to 120, 2 weeks ago. Will probably be "undectable" soon. My question is, my... Read more »