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Reaction To Peg-intron

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AIDSinfo

An Overview of Ziagen (Abacavir)

...day.Some individuals may benefit from different doses of abacavir sulfate. Individuals should always take abacavir sulfate as prescribed by their doctors. Contraindications Individuals who have experienced a serious allergic reaction (hypersensitivity reaction) to abacavir sulfate (in Ziagen, Epzicom, or Trizivir) should not take this medicine. Individuals who test positive for HLA B*5701, a genetic marker for the hypersensitivity...
Ask the Experts

Peg-Intron and Pegasys

What are the differences between Peg-Intron Alpha 2b and Pegasys??
Maribel Rodriguez-Torres, M.D.

Response from Maribel Rodriguez-Torres, M.D.

Fundacion Gatroenterologia De Diego
The difference is mainly the type of Peg ,or polyethilene glycol moeity that is added to the interferon alfa.Peg Intron has a small lineal 12kd chain and Pegasys has a large ,branched ,heavy 40kd,chain.The larger molecule stays in the liver,is less... Read more »

Peg intron or Pegasys?

I've recently started the peg-intron-rebitol combo. Should the Peg not work for me is there any data that reveals the new Pegasys drug, due to be approved next year, provide me any hope of eradicating the virus?...My Dr tells me I'm genotype 1a with...
Maribel Rodriguez-Torres, M.D.

Response from Maribel Rodriguez-Torres, M.D.

Fundacion Gatroenterologia De Diego
...There is no data of Peg-Intron/RBV non responders with Pegasys.The data on Peg-Intron/RBV in genotype 1,is sustained responses of 41%,vs.46% with Pegasys/RBV.If Read more »

What is the difference between Pegsys and Peg Intron

Hi Doctor Dieterich: Is it true that Pegintron and Pegsys are the same! I was told by my doctor that they are exactly the same except one is made in the US and one made in Swiss. Are there any difference?Thank you sir for your time.
Douglas T. Dieterich, M.D.

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine
They are pretty close. Pegasys has a longer half life of about 75 hours, versus 54 hours for Peg Intron. Pegasys is excreted mostly in the liver while Peg Intron mostly in the kidney. The overall success rates for the two are almost exactly the same... Read more »

Pegasys to Peg-Intron?

Dear Dr.If you relapse after Pegasys do you recommend switching to Peg-Intron the next time? I hear the sides are much worse.Thanks
Douglas T. Dieterich, M.D.

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine
I usually recommend switching brands, although there is no real scientific reason to do so. The side effects are comparable and now you know what to expect. Anytime you treat again, if you did get undetectable the first time, the chances are really... Read more »
Articles
AIDSinfo

An Overview of Peginterferon Alfa-2 (Pegasys, PEG-Intron)

... peg-in-ter-FEER-on Brand Name: PEG-Intron (2b), Pegasys (2a) Other Name(s): pegylated interferon Drug Class: Opportunistic Infection and Other Drugs Peginterferon Read more »
The Body PRO

Salvage Therapy

...Thirteen "flu-like symptoms," fevers, myalgias, etc. Six neuropsychiatric symptoms Three bone marrow toxicity One allergic reaction One altered sense of smell The authors concluded that PEG-Intron at doses of 1.0, 1.5 and 3.0 mcg/kg weekly... Read more »
Brown Medical School

HCV in Corrections: Frontline or Backwater?

...cost-effective screening test; recombinant immunoblot assay (RIA) helps confirm positive EIA results, while polymerase chain reaction (PCR) is the "gold standard" for confirming active HCV infection with viral replication. In rare cases, the HCV... Read more »
San Francisco AIDS Foundation

Drug Watch: Nanotechnology for Antiretroviral Delivery

...reaches in the body after dosing, while AUC reflects the total concentration of a drug over time between doses. Injection site reactions consisting of redness, bruising, pain, and in some cases induration (hard swelling) were more common with... Read more »
Connect With Others

my strange reaction

Posted by midwestguy143, 2 Replies
...I tested positive on March 24, 2009. The thing that surprised me, and my friends was my reaction -- none really. Just something else in my life. I had lost my job many months ago, and with the job market being so tough, Read more »

started meds and hate it.

Posted by frank74, 9 Replies
I started meds because my vl was too high 100,000 and cd4 dropped to below 500. I don't have any physical issues with meds but I is more emotional. It's a twice daily reminder of it(HIV) that before I could forget about it for a while. Read more »

allergic reactions

Posted by TRex, 2 Replies
...Has anyone who is HIV positive had a lot of allergic reactiosn to antibiotics? I had two allergic reactions (the Bactrim one was the one who made me ask for the HIV test).the other one is Keflex. I am on Augmentin now and woke up with Read more »

Some drug reactions, I think

Posted by ScotCharles, 1 Reply
Hey guys, long time no parlez, For two years I've been on a regimen of Norvir, Atazanavir (Reyetaz) and Truvada (Viread and Emtriva). Last July I developed tingling in my toes (parathesia) which became painful buring and shooting pains. This... Read more »