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Reaction To DdI

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Taking Current Antiretroviral Drugs

... Abacavir (Ziagen) 2 (300 mg: 1, 2x/day or 2, 1x/day) No food restrictions; alcohol boosts abacavir levels. Hypersensitivity reaction in about 8% of patients Don't use with ust two other nucleoside analogs unless additional drugs are used. Combivir (Combination pill) 2 (150 mg lamivudine + 300 mg zidovudine: 1, 2x/day) No food restrictions. Anemia, nausea, vomiting, headache, fatigue, muscle aches, bone marrow toxicity,....
Ask the Experts

heppatitis from drug

I have azt+ddi+norvir+crixivan sinc oct 2000. Then change to combivir+sustiva sinc jan 2002. 2 weeks ago I got sick doctor said have hepatitis but the test result for hva hvb hvc and cmv are all negative. I think it effect of my hiv drug and I stop...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine your define liver irritation. I would doubt that the Combivir triggered that reaction since you previously were on AZT + ddI OK. You should be able to go back to your previous PI based therapy. Use of abacavir or tenofovir might also be... Read more »

DDI vs D4T

I have excellent results on D4T/3tc/Nevirapine (1200 CD4/ 40/<50 copies sustained for some time).I have been on treatment for 2 years. Tried swapping D4T for AZT but had a bad reaction.The other day my doc suggested I could simplify my regime if I...
Judith A. Aberg, M.D.

Response from Judith A. Aberg, M.D.

Washington University, St. Louis School of Medicine
...reasonable option. I do not know what side effects you had from AZT or why you stopped D4T. That would be useful information. DDI can have significant side effects besides just the nausea and sometimes vomiting. It is associated with... Read more »

DDI questions

Why would my doctor perscribe the chewable twice daily tablet rather than the capsule? Is there any reason other than maybe he did not know about the capsule?I have taken DDI in mid 90s and I quit taking it because it made me sick. I got a huge hump...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
...only 9% at 48 weeks, which is very low for any antiretroviral regimen. I agree that there is little reason for using Videx (didanosine) tablets now that Videx EC is available. It is much better tolerated, and many of my patients who didn't... Read more »

Restarting Abacavir after Drug Holiday

I plan to re-start my meds after a three-month drug holiday. I recently read some reports of trouble that some people had after going back on Abacavir (Ziagen) after drug holidays (aka structured treatment interruptions). It seems some of those...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...long as it is done carefully with rapid access to your doc if you have any problems suggestive of the abacavir hypersensitivity reaction. Good luck! KHKeith Henry, M.D. Read more »
AIDS InfoNet

Stavudine (Zerit)

...drugs and supplements you are taking. Stavudine should not be taken with AZT (zidovudine, Retrovir®) or didanosine (ddI, Videx®). Stavudine's side effects may be worse if taken with ganciclovir or pentamidine. Pregnant women should... Read more »
AIDS InfoNet


...provider before taking any form of pentamidine. How Does Pentamidine Interact With Other Drugs? You may need to stop taking ddI (see Fact Sheet 413 ) when you take pentamidine. The Bottom Line When the first-choice treatments for... Read more »
AIDS InfoNet

Dapsone (Avlosulfon)

...reduced if you take rifampin , a drug used to treat tuberculosis (see Fact Sheet 518 ) or MAC (see Fact Sheet 514 ). Also, ddI can reduce absorption of dapsone. Take dapsone at least 2 hours before or after you take ddI . The risk of... Read more »
The Well Project

HIV Drugs and the HIV Lifecycle

...As the smaller protein pieces come together with copies ofHIV's RNA, a new virus is put together (assembled). Budding The newly-assembled virus pushes ("buds") out of the original CD4 cell.This new virus is now able to... Read more »
Connect With Others

HIV is not for sissies

Posted by ScotCharles, 3 Replies
...time with an allergic reaction to Bactrim, and once with Viread related pancreatitis. I have taken AZT, epivir, zerit, DDC, DDI, sustiva, videx, viread, truvada, norvir, atazanavir, prezista, and issentress. Many of those meds had very... Read more »

Does anyone feel good on meds??

Posted by Anonymous, 6 Replies
I found out I was HIV pos last year. Doing well, feeling great, normal CD4 and percentages and VL less than 1500 on three tests. No meds needed yet per my HIV doc. Reading the posts here and letters to the experts it seems everyone is having... Read more »

I just started taking meds...

Posted by Anonymous, 6 Replies
and would love some feedback from people. I was poz for 3 yrs before needing to begin and since I am moving to Costa Rica in the fall I thought 'no time like the present' to get myself trhough all the possible side effects. Well- they have begun. ... Read more »


Posted by Anonymous, 1 Reply
...infections. This class of drugs, called nucleoside analogs, include * AZT (Azidothymidine) * ddC (zalcitabine) * ddI (dideoxyinosine) * d4T (stavudine) * 3TC (lamivudine) * Abacavir (ziagen) * Tenofovir (viread) *... Read more »