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Reaction To Ziagen

Here's a taste of what has to offer on this topic:
Ask the Experts

Ziagen Reaction?

...but after reading an article in POZ Magazine I am slightly concerned. The article said that some people may have an allergic reaction to Ziagen & not even know it -- nausea and GI problems were definitely a symptom of the syndrome. Should I be...
Andrew T. Pavia, M.D.

Response from Andrew T. Pavia, M.D.

University of Utah, School of Medicine
...The problems associated with Ziagen are in the form of something called "hypersensitivity syndrome" It is most likely a form of immune mediated reaction, but it Read more »

Halting Ziagen

How does one decide which of 4 drugs are causing side effects when it could be any of them? Regimen... Read more »

Ziagen - Rash

...this... Are there any reported cases of an allergic reaction to Ziagen developing later in the... Read more »
U.S. Food and Drug Administration

Important Drug Warning: Severe Hypersensitivity Reactions Following Reintroduction with ZiagenĀ® (Abacavir Sulfate) Products

...the treatment of HIV-1 infection. Fatal hypersensitivity reactions are a described risk associated with the use of abacavir (Ziagen); patients who have developed hypersensitivity reactions upon abacavir rechallenge are at an increased risk of a... Read more »
Test Positive Aware Network


...avoided with a genetic test to screen out those predisposed to have it. However, patients should be vigilant about any possible reactions (like rash) when starting this drug and let their doctor know immediately. The second strike is a little... Read more »
Test Positive Aware Network


...analogs (also called nucleoside reverse transcriptase inhibitors, NRTIs or nukes) Standard dose: One tablet (300 mg Ziagen/ABC/abacavir, 150 mg Epivir/3TC/lamivudine, and 300 mg Retrovir/zidovudine/AZT), twice a day, with or without... Read more »
Test Positive Aware Network


...The incidence of HSR was the same between Epzicom once-daily and Ziagen twice-daily (8% vs. 9%), but the incidence of severe reactions was higher with Epzicom (5% vs. 2%). Remember that the HSR cited may have been suspected, not definitely... Read more »
Connect With Others

Body rash

Posted by Anonymous, 1 Reply
Has anybody else experienced a slight whole body rash with HIV? My skin appears to be slightly more red and itchy now. This can be seen throughout the body. Read more »

Abacavir - Hypersensitivity - EPZICOM

Posted by Survivor, 2 Replies
...hypotension, adult respiratory distress syndrome, respiratory failure, and death have occurred in association with hypersensitivity reactions. In one study, 4 patients (11%) receiving ZIAGEN 600 mg once daily experienced hypotension with a... Read more »

Back on Meds--Almost

Posted by Blixer, 6 Replies
Well my doctor determined that he thinks my problem was with the Abacavir in the Epzicom. So he gave me two options. Replace the abacavir with Videx and leave everything else the same or also drop the Sustiva and go to a Boosted Reyataz. I choose... Read more »


Posted by Anonymous, 4 Replies
...drug, including asking you to carry a Warning Card with you at all times that details potential life threatening reactions. I also have only found research study showing 24 weeks of follow up on naive patients.... Read more »