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Reaction To Telzir

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An Overview of Lexiva (Fosamprenavir, Telzir)

FOS-am-pren-a-veer Brand Name: Lexiva Other Name: FPV, fosamprenavir calcium Drug Class: Protease Inhibitors Approved Use: Treatment of HIV Infection WARNING: Fosamprenavir can cause serious, life-threatening side effects. These include severe skin reactions or rash. If you get a rash with any of the following symptoms, stop taking fosamprenavir and contact your health care provider or get medical help right away: ...
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Viread/Emtriva/Norvir/Telzir as first line treatment?

Hello, a friend of mine with a VL of about 400,000 and about 200 CD4s was suggested the following first line treatment: Tenofovir, Emtricitabin, Ritonavir and Fosamprenavir. I wonder whether this makes sense since the gold standard is...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
James, thanks for your post.First off, you are correct in the statement that Combivir + Kaletra or Combivir + efavirenz are among the preferred regimens in contemporary guidelines. There is a lot of very long-term data with either of these two... Read more »

Switching to Lexiva/Telzir, Norvir and Truvada

Two years ago I've started taking Kaletra and Combivir. It works very fine for me, nearly without any side effects, my virus load is undetectable and my CD4-count raised from 150 up to 430. Unfortunately my cholesterol levels are relatively...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post and kind words.With the arrivals of atazanavir (Reyataz) and fosamprenavir (Lexiva, Telzir), we're seeing a resurgence in the use of first-line protease inhibitors.The proposed regimen of fosamprenavir/ritonavir with... Read more »

muscle and bone pain

dear doctor,thank you for answering this question. I am on treatment: morning telzir/norvir, emtriva and viread. Evening: telzir/norvir. Also I take coversyl for my blood pressure. But since 6 months I have terrible pains in the morning. My muscles...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
You need to have a through clinical evaluation to assess more precisely whether bones, muscles, or joints are the site of the pain. Labs and sometime X-ray evaluation may also be needed. Fosamprenavir rarely causes bone/muscle pain (also true of the... Read more »

Changeover to Etravirine

Hi, I am about to change my regime from Truvada and Telzir to Truvada and Intelence. I was told that I can do a straight switch, but I note from the information on Intelence that the Telzir/fosamprenavir should not be taken at the same time. Does...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Though there is concern about somewhat unpredictable interactions between fosamprenavir and etravirine when used together. For a simple switch from one to another I would be less concerned (I would be concerned if your viral load is not undetectable... Read more »

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